Klebsillla Flashcards
The 3 types of klebsiella
Penumonia-oxytoca- granulomatis
virulence factors
1) adhesions 2) o antigen lipopolyscahride 3) K antigen capsular polysaccharides 4) siderophores
Klebsiella are——-
Ubiquitous in nature
In humans, klbsiella colonize the—-
Skin- pharynx- GI tract
Klebsiella can have both
Community (elderly and alcoholics) vs hospital (8-10 of infections)
cklinical diseases caused by klebsiella
9hene 5)
Slide 21
All strains of K pneumonia are resistant to
Ampicillin because they have a beta lactase gene that is penicillan specific
SERATIA SPECIES fee 2 types:
Serratia marcescens Serratia liquefaciens
They survive in:
Harsh conditions even some disinfectants i
Infections by S marscenes bigness with
begin with exogenous contamination
and spread within or among hospitals on the hands of Personnel
The most common source of infection for serratia is:
UTI but they’re also isolated from resp and wounds 2%HAI
They produce
Beta lactamase
They can causd
Bacteremias leading to complications
Enterobacter properties
Capsule/ beta lactamase producers/
Enterobacter strains commonly arise from
1) endogenous flora from hospitalized patients
2)common source outbreaks
3) patient to patient
Enterobacter spp. may cause a wide variety of nosocomial infections, including
1) pneumonia 2) UTI 3) meningitis 4) wound and burn infections 5) Infections of intravascular and other prosthetic devices
species of enterbacter:
Enterobacter cloacae
Enterobacter aerogenes
Enterobacter sakazakii
citrobacter species:
(BETA LACTMASE PRODUCER)
Citrobacter freundii
Citrobacter koseri (formerly Citrobacter diversus)
Citrobacter amalonaticus
——is the most frequent site from which citrobacter is isolated often in association with—. citrabcter may also be isolated from—-a finding which
urinary tract/indwelling catheter/ resp tract/ usually correlates to colonization rather than symptomatic infection
Citrobacter is usually found in:
1) urinary tract (indwellng catheter)
2)resp tract — colonization rather than symptomatic infection
3) intra-abdominal infections
4) soft tissue infections and osetomyelitis
5) invasive prodcedures may lead to citrobacter bactermia
C. koseri
can cause an ususual severe form of neonatal meninigitis asociated with necrotizing encephalitis (inflammation of the brain,)and brain abscesses
Providencia stuartii is found as commonly as
more familliar urinary tract isolates
Morganella morganii is an
infreuquent nosocomial isolate usually isolated from urine or wounds
which 4 types of bacteria are occasional and transient enterbavteria of the digestive tract?
enterbacterai, citro, sarratia, motganella
w shu 8er 3an hol bacteria?
they are opportunistic in case of nosocomial infections (imunocompomised and newborns) w they are probeklmatic naturally resistant to several antibiotics
(ampicillin, cephalosporin..)
what are the 2 types od bacteria that u think of when u think of nosomial?
enterbacter and morganella
the 2 species of proteus
mirabilis and mirabilis
proteus are
urease producer microoranisms and they are swraming bacteria
the ability of proteus to—
produce urease and to alkalinize the urine by
hydrolyzing urea to ammonia survive in environment precipitation of organic
and inorganic compounds struvite stone formation (ammonium phosphate +
calcium carbonate)
most coomin infectiosn due to proteus
UTIs occasionally in nomrla hosts and most commonly in those with
indwelling catheters or anatomic or functional abnormalities of the urinary tract
so when u think of proteus think of— and –
kidney stones and UTIs
types of UTIs caused by proteus:
1)Urethritis
2), Cystitis (inflammation of bladder)
3) Pyelonephritis, (kindey infection)
4)Prostitis post infection (history of UTI infection)
Proteus spp. Are commonly isolated from the ——-the vast majority
secondary (due to)—, often associated with urinary catheters
bloodstream/UTI
flaschards
