ESBL

Question 1

ESBL means

Answer 1

extended spectrum beta lactamase prodducers

Question 2

they are—and they execrete—which inactiavtes

Answer 2

gram negative/enterobactaice / the enzyme beta lactamase/beta lactam (penicillin) type antibiotics

Question 3

resistance to beta lactams emerged —and —

Answer 3

several years ago and has continued to rise

Question 4

ESBLS are:

Answer 4

klebsiella/ E coli/serratia/ others

Question 5

ESBLs are eznymes that mediate resistance to—but do not affect—

Answer 5

extended spectrum (third gen) cephalosporins (ex: ceftazidime, cefotaxime, and ceftriaxone) and monobactams (aztreonam) /ceffamycin (cefoxitin and cefotetan) OR carbapenems ((e.g., meropenem or
imipenem).

Question 6

ESBLs are often located on—

Answer 6

plasmids that are transferable from strain to strain between bacterial species

Question 7

beta lactamase ihibitos like—generally—-

Answer 7

clavulanic acid/ ESBL producing strains

Question 8

resistance genes associated with ESBL

Answer 8

TEM
SHV
CTX-M
OXA could hydrolyze oxacillin and related anti-staphylococcal penicillins.
Poorly inhibited by clavulanic acid
AMP-C