Kızıltunç

Question 1

Define the most notable characteristic difference with regard to AMP-activated protein kinase (AMPK) between ATP-consuming processes and ATP-producing processes.

A) AMPK increases transport

B) AMPK increases muscle contraction

C) AMPK increases growth promotion

D) AMPK increases oxidation of glucose

E) AMPK increases biosynthesis

Answer 1

D) AMPK increases oxidation of glucose

Question 2

All are associated with characterization of the cancer cells, except:

a) Limitless replicative
b) Regular apoptosis
c) Increased telomerase activity
d) Angiogenesis
e) Metastasis

Answer 2

b) Regular apoptosis

Question 3

Phosphorylation of ………………. by cyclin-dependent protein kinases releases the transcription factor E2F/DP from Inhibitory control and then the transcription of genes starts in cell cycle progression.

a) Phosphoinositide 3-kinase
b) Retinoblastoma

C) protein Mitogen activated protein

d) Protein kinase B
e) Transforming growth factor beta

Answer 3

b) Retinoblastoma

Question 4

Choose the false:

a) White adipose tissue synthesis the huge leptin hormon
b) Brown adipose tissue expressions the heat and lipid oxidation

C) White adipose tissue contains a few mitochondria

d) White adipose tissue synthesis the high level uncoupling protein
e) Brown adipose tissue is active in the neonate

Answer 4

d) White adipose tissue synthesis the high level uncoupling protein

Question 5

In a biochemistry laboratory, if blood is centrifuged after collecting blood in a tube containing anticoagulant, what is the name of the clear liquid that remains on top?

a) Plasma
b) Whole blood
c) Hemolysate
d) Serum
e) Hypotonic

Answer 5

a) Plasma

Question 6

Plaque formation is related with all of them, except:

a) Physical activity
b) Smoking
c) Climate change
d) Oxidative stress
e) Food intake

Answer 6

c) Climate change

Question 7

All are increased with the leptin, except:

a) Energy expenditure
b) Melanosit stimulating hormon (MSH)
c) Sympathetic nervous activity
d) Proopiomelanocortin (POMC)
e) Food intake

Answer 7

e) Food intake

Question 8

Which of the following is decreased with the increased body mass index?

a) Mortality
b) Obesity
c) LDL-C
d) Cardiovascular diseases
e) HDL-C

Answer 8

e) HDL-C

Question 9

What kind of kinases enzyme is present throught the cell cycle?

a) Cytosolic Phosphoenol pyruvate kinases
b) Nucleus Hexokinases
c) Cyclin dependent protein kinases
d) Cycle Phosphofructokinases
e) PEP-carboxykinases

Answer 9

c) Cyclin dependent protein kinases

Question 10

Which of the following parameters cannot be studied in the hemogram device in the biochemistry laborator

a) Leukocyte count (WBC)
b) Prothrombin time (PT)

C) Hemoglobin (HGB)

d) Hematocrit (HCT)
e) Red blood cell count (RBC)

Answer 10

b) Prothrombin time (PT)

Question 11

Choose the false:

a) Proteine kinase B stimulates the apoptosis
b) Adenomatous polyposis coli (APT) is a tumor suppressor protein
c) Beta-catenin binds to the transcription factor TCF.
d) Viral oncogene E6 binds to p53 protein
e) Beta-catenin stimulates the expression of cyclin D1 and Myc proteins

Answer 11

a) Proteine kinase B stimulates the apoptosis

Question 12

body mass index’s normal value

Answer 12

18-25

Question 13

increased blood leptin level is not result in …

increased energy synthesis

Answer 13

increased energy synthesis

Question 14

where does ghrelin hormone syntesis from…

Answer 14

stomach

Question 15

The cell cycle has four stages including G1, S, G2 and M phase. With each return of the cell cycle is synthesized ……………. via the cyclin and cyclin-dependent kinases compound

Answer 15

DNA, RNA and protein in the S phase

Question 16

Which of the following statement concerning (about) cell cycle is correct

– Retinablastoma protein (RB) joins to elongation 2 factor (E2F) and dimerization partner (DP) in the G1 phase

Answer 16

– Retinablastoma protein (RB) joins to elongation 2 factor (E2F) and dimerization partner (DP) in the G1 phase

Question 17

Human cancer cells have some biochemical and genetic changes in the body. Which one is not found in cancer cells

– Decreased telomerase activity

Answer 17

– Decreased telomerase activity

Question 18

Cancer cells are characterized by common key factors. Which of the following is not associated with characterization of the cancer cells

– Regular apoptosis

Answer 18

Regular apoptosis

Question 19

Modification of plasma ghrelin, insulin and glucose are often associated with breakfast, lunch, dinner and snack periods. Rise of the blood ghrelin level occur …………..

Answer 19

– Before meals

Question 20

Blood is taken to an anticoagulant tube and allowed to stand for 5-10 minutes at room temperature. The tube is than centrifuged. What is the liquid in the upper part?
A]Serum
B]Plasma
C]Whole blood
D]Hemolysate
E]Isotonic

Answer 20

B]Plasma

Question 21

Which of the following is not present in the serum? 
A]Fibrinogen
B]Albumin
C]Alpha golobulin
D]Beta globülin 
E]Gamma globülin

Answer 21

A]Fibrinogen

Question 22

Which one is related to GTPase activity in RAS?

Answer 22

neurofibromin

Question 23

Which one happens in RAS mutation?

Decreases the nuclear synthesis of cyclin d1

Answer 23

Decreases the nuclear synthesis of cyclin d1

Question 24

Which one causes Tuberoscleroz?

Answer 24

Hamartin tuberin

Question 25

Which one defective (mutated) in achondroplasia?

Answer 25

Fibroblast growth factor receptor

Question 26

Which one is hemogram tube?

Answer 26

EDTA tube with purple cap

Question 27

Which one is not related to plaque formation?

Answer 27

climate change

Question 28

Increases energy expenditure……. decreses………

Answer 28

Leptin and ghrelin

Question 29

Which one is not related to apoptosis?

Retinoblastoma protein

Answer 29

Retinoblastoma protein

Question 30

Which one is tumor suppressor gen?

Nuclear phosphoprotein p53

Answer 30

Nuclear phosphoprotein p53

Question 31

Pıhtılaşan tam kanı santrifüj edince üstte kalan?

Answer 31

Serum