Hamidullah Flashcards
Which of the following is the major opsonin of the complement system?
A) C1grs
B) C3b
C) Mannose Binding Lectin
D) C1INH
E) C5b6789
B) C3b
23.(Mikrobiyoloji pratik) Aşağıdakilerden hangisinde radyoaktif maddelerle işaretli antikor kullanılır?
(Microbiology practice)
Which of the following method radioactive labeled antibody used?
A) ELISA
B) ANA
C) IFA
D) LIA
E) RIA
E) RIA
Which of the following chemical substance is
generally not immunogenic?
A) Polysaccharides
B) Proteins
C) Phospholipids
D) Nucleic acids
E) Lipids
E) Lipids
Reaction of antibodies and soluable antigens in an in-vitro test is referred to as:
A) Complement Fixation
B) Agglutination
C) Precipitation
D) Coagulation
E) Antigen presentation
C) Precipitation
(Mikrobiyoloji pratik) Aşağıdaki si lajik yöntemlerden hangisinde çözünür antgenler taşıyıcı partikül olarak yapay sentetik madde yüzeyine bağlanarak kullanılır? (Microbiology practice) Which of the following serological method soluble antigen use with chemically link artificial synthetic substance?
A) Hemaglütinasyon/ Hemagglutination
B) Lateks aglutinasyon/Latex agglutination
C) Kompleman fiksasyon/Complement Fixation
D) Wright aglutinasyon/Wright agglutination
E) Koaglutinasyon/Coagglutination
B) Lateks aglutinasyon/Latex agglutination
In the human disease known as lupus, there is an immune reaction against a patient’s own DNA from broken or dying cells. This kind of response typifies which kind of irregularity?
A) allergy
B) immunodeficiency
C) autoimmune disease
D) antigenic variation
E) cancer
C) autoimmune disease
Which of the following hypersensitivity reaction type also known as T-cell-mediated delayed Hypersensitivity reaction?
A) Type I
B) Type II
C) Type III
D) Type IV
E) Type V
D) Type IV
Which of the following substance can non-specifically enhance the immune response when it is injected with the antigens?
A) hapten
B) antigen
C) paratope
D) adjuvant
E) cytokine
D) adjuvant
Which statement about the complement system is true?
A) These proteins are involved in innate immunity and not acquired Immunity.
B) These proteins are secreted by cytotoxic T cells and other CD8 cells.
C) This group of proteins includes interferons and interleukins.
D) These proteins are one group of proteins acting together in cascade.
E) These proteins act individually to attack and lyse microbes.
D) These proteins are one group of proteins acting together in cascade.
Which of the following test antigen detected with dye labelled antibody on the surface of slide?
A) Enzyme-Linked Immunosorbent Assay
B) Hemagglutination tests
C) Complement Fixation tests
D) Radioimmunoassay tests
E) Direct Immunofluorescence test
E) Direct Immunofluorescence test
Which of the following test antigen detected with labelled antibody?
A)Immunofluorescence
B) Complement Fixation
C)Agglutination
D) Hemagglutination
E) Precipitation
A)Immunofluorescence
Which of the following is describe a low molecular weight compounds that can be made immunogenic by conjugation to a suitable carrier?
A) paratope
B) hateroantigen
C) adjuvant
D) hapten
E) alloantigen
D) hapten
(PRATİK)Çözünür antijenlerin taşıyıci partikul olarak yapay sentetik madde yüzeyine bağlandığs serolojik yöntem aşağıdakilerden hangisidir? (Microbiology practice) Which of the following serological method soluble antigen use with chemically
link artificial synthetic substance?
A) Lateks aglutinasyon/Latex agglutination
B) Hemaglutinasyon/Hemagglutination
C) Wright aglutinasyon/Wright agglutination
D) Kosglutinasyon/Coagglutination
E) Kompleman fiksasyon/Complement Fixation
A) Lateks aglutinasyon/Latex agglutination
Which of the following complement binds to call membrane last and cause functional pore formation?
A) C9
B) C5
C) C6
D) C7
E) C8
A) C9
Which of the following is more active Anaphylatoxin?
A) C5b6789
B) C3b
C) C5a
D) C1qrs
E) MBL
C) C5a
Which of the following describes a state of unresponsiveness of the immune system to substances or tissue?
A) autoimmune disease
B) allergy
C) antigenic variation
D) Immune tolerance
E) hypersensitivity
D) Immune tolerance
Which of the following factor affecting immunogenicity of antigen is false?
A) proteins are more immunogenic
B) monomers are more immunogenic
C) adjuvant increase the immunogenic affect
D) big molecules (>6.000 dalton) are generally more immunogenic
E) foreignness increase the immunogenic affect
B) monomers are more immunogenic
(PRATIK)Aşağıdakilerden hangisi işaretli antikor yöntemlerinden değildir? Which of the following method is not a labeled antibody technique?
A) Radioimmunoassay Radioimmunoassay
B) Kompetitif ELISA/ Competitive ELISA
C) Indirekt ELISA/ Indirect ELISA
D) Wright aglutinasyon/Wright agglutination
E) Indirekt immunfloresan antikor/Indirect Immunofluorescence test
D) Wright aglutinasyon/Wright agglutination
Which of the following hypersensitivity reaction type also known as Cytotoxic antibody mediated immunity?
A) Type V
B) Type lII
C) Type IV
D) Type I
E) Type II
E) Type II
Which of the following test sheep RBC and antibody to sheep RBC use as an indicator?
A) Precipitation
B) Western Blot
C) Radioimmunoassay
D) Hemagglutination
E) Complement Fixation
E) Complement Fixation
Which of the following hypersensitivity reaction is IgE mediated?
a) Type I
b) Type II
C) Type IV
d) Type V
e) Type III
a) Type I
Antibody specifically binds to antigen by their……….. part.
a) convertase
b) Fc
C) C3
d) epitope
e) Fab
e) Fab
Which of the following test based on the formation of an insoluble particles by forming optimal combination of soluble antigens with specific antibodies, that it can be seen with the naked eye?
a) Gruber Widal test
b) Neutralisation test
C) Precipitation test
d) Complement Fixation test
e) Hemagglutination test
C) Precipitation test
Which of the following condition mainly occur when the immune tolerance is disrupted.
a) antigenic variation
b) allergy
C) autoimmunity
d) hypersensitivity
e) Immunodeficiency
C) autoimmunity
Which of the following test labelled antibody use to detect autoantibody on a surface of slide?
a) Precipitation tests
b) Latex agglutination tests
C) Indirect Immunofluorescence test
d) Complement Fixation tests
e) Radioimmunoassay tests
C) Indirect Immunofluorescence test
Which of the following is define the C5b6789 structure?
a) Mannose Binding Lectin
b) Histamine
C) MAC complex
d) Complement system inhibitors
e) C10 Convertase
C) MAC complex
Bacterial Capsular Polysaccharide antigens are described as …….
a) “H” antigens
b) “Vi” antigens
c) “O” antigens
d) “K” antigens
e) “M” antigens
d) “K” antigens
Which of the following serological method is performed by tube agglutination method?
a) Precipitation test
b) Coagglutination
c) Capture ELISA
d) Wright test
e) Neutralisation test
d) Wright test
Which of the following, bacterial toxins that interact with immunoreceptors, T cell receptor (TCR) and major histocompatibility complex (MHC) class II. conventionally through the variable B-domain of TCR (TCRVB) and induce massive release of cytokines.
a) alloantigen
b) heteroantigen
C) autoantigen
d) heterophile antigen
e) superantigen
e) superantigen
Which of the following complement protein have a role in alternative pathway?
a) Mannose Binding Lectin
b) Factor B
C) C2
d) C4
e) C1qrs
b) Factor B
which immunoglobulins shows the efficiacy in the secondary immune response
Ig G
Regarding haptens, which one of the most accurate..
a hapten can not induce antibody
by itself but can do so when covalently bound to a carrier protein
a hapten can not induce antibody
by itself but can do so when covalently bound to a carrier protein
which method radioactive labeled antibody use in laboratory diagnosis
RIA
Which serologic method soluble antigen use with chemically link artificial synthetic substances
latex agglugination
Which of the complement binds to the antigen antibody complex at the beginning of the classical pathway
C1
Which is more active anaphylatoxin
C5a
which is related with t-cell-mediated delayed hypersensitivity reactio
type 4
A state of unresponsiveness of the immune system to substances or tissue is known as..
immune tolerance
According to sources of the antigens which of the following defines antigen found in different individuals of the same species
allo antigen
Which of the following is an agent often used to modify or augment the effects of a vaccine by stimulating the immune system
adjuvant
Which one is the method when soluble antigen and antibody combines and
becomes visible?
Precipitation
Which method, ELISA and electrophores together?
Western blot
Which one is MAC?
C5b6789
Which one is bacterial somatic antigen?
O antigens
With which one does the classic pathway start?
C1
?.???.?37.Which one is labeled test? Neutralization
?
Which hypersensitivity reaction does complex deposition?
Type 3
Which one is antigen found in different individuals, same species like ABO system?
Allo antigen
Which of the following mediates Type I hypersensitivity reaction?
A) IgA
B) IgD
C) IgE
D) IgG
E) IgM
C) IgE
Which of the following test antigen detected with dye labelled antibody on the surface of slide?
A) Radioimmunoassay tests
B) Latex agglutination tests
C) Complement Fixation tests
D) Precipitation tests
E) Direct Immunofluorescence test
E) Direct Immunofluorescence test
The classical activation pathway is initiated by binding of which complement to the antigen-antibody complex?
A) C1
B) C2
C) C3
D) C5
E) MBL
A) C1
(PRATIK) Aşağıdakilerden hangisi işaretli antikor yöntemlerinden değildir? Which of the following method is not a labeled antibody technique?
A) Indirekt ELISA/Indirect ELISA
B) Turbidimetrik yöntem/ Turbidimetric method
C) Indirekt immunforesan antikor/Indirect immunforesan test
D) Kompetir ELISA /Competitive ELISA
E) Redlonmanoessay/Radioimmunoassay
B) Turbidimetrik yöntem/ Turbidimetric method
Which of the following method is used for confirmation of positive ELISA results?
A) Complement Fixation
B) Western Blot
C) Viral Hemagglutination
D) Wasserman test
E) Passive Agglutination Test
B) Western Blot
50.Which of the following autoimmune disease is related molecular mimicry with induction of the disease dependent upon an immune response to a Streptococcal cell wall antigen cross reacting with a myocardial antigen?
A) Systemic Lupus Erithematosus
B) Hashimoto’s Disease
C) Sjogren’s Syndrome
D) Rheumatic Fever
E) Multiple Sclerosis
D) Rheumatic Fever
Which of the following property is not related with systemic autoimmune disease?
A) Widespread self-antigens are targets for autoimmune attack
B) Damage affects such structures as blood vessels, cell nuclei etc.
C) Treatment is aimed to inhibit excessive activation of the immune system
D) Also known as Non organ-specific autoimmune disease
E) Autoimmune attack versus self-antigens of given organ
E) Autoimmune attack versus self-antigens of given organ
(PRATİK)S.aureus’un dış yüzeyinde bulunan protein A’ya doğal olarak antikorların Fc kısmının bağlanması esasına dayalı serolojik yöntem aşağıdakilerden hangisidir? Which of the following serological method is based on naturally adsorbs the Fc portion of the antibody to the protein A distributed cell wall component of S. aureus?
A) Hemaglütinasyon/Hemagglutination
B) Lateks aglutinasyon/Latex agglutination
C) Kompleman fiksasyon/Complement Fixation
D) Wright aglutinasyon/Wright agglutination
E) Koaglutinasyon/Coagglutination
E) Koaglutinasyon/Coagglutination
(PRATİK)Direkt Floresan Antikor tekniği ile aşağıdakilerden hangisinin varlığı araştırılır?
Direct Fluorescent Antibody Technique detects the presence of what immune-related protein?
A) Lateks partikülleri/Latex particles
B) Presipitatlar/Precipitates
C) Antijenler/Antigens
D) Komplemanlar/Complements
E) Antikorlar/Antibodies
C) Antijenler/Antigens
(Mikrobiyoloji PRATIK) Aşağıdaki serolojik yöntemlerden hangisi tap aglutinasyon yöntemi ile yapılır?
(Microbiology practice) Which of the following serological method is determined by tube agglutination technique?
A) ELISA/ELISA
B) Immun floresan antikor testi/ Immunofluorescence test
C) Notralizasyon testi/Neutralisation test
D) Presipitasyon testi/Presipitation test
E) Wright aglutinasyon testi/ Wright agglutination test
E) Wright aglutinasyon testi/ Wright agglutination test
The Lectin Pathway is initiated when the immune systern recognizes
A) lectin on microbes
B) mannose on microbes
C) an antibody on microbes
D) C5a on microbes
E) C1 on microbes
B) mannose on microbes
If blood transfusion is made from a black man to a white man, what kind of an antigen has been given to recipient.
A) Hetero antigen
B) Allo (iso) antigen
C) Heterophile antigen
D) Auto antigen
E) Common antigen shared by different species
B) Allo (iso) antigen
Microbial antigens that are similar to self- antigens can active T and B cells producing cross-reacting immunoglobulin’s is
A) apoptosis
B) molecular mimicry
C) allergy
D) antigenic variation
E) anergy
B) molecular mimicry
Mark the correct statement. Adjuvants are;
A) Substances with a weak antigenic effect.
B) Substances that can elicit an immune response only when attached to a protein carrier.
C) The distinct portion of the antigen molecule which known as the “determinant site”.
D) Substances that, when mixed with an antigen and injected with it, enhance the immunogenicity of that antigen.
E) Immunologically active regions of an antigen molecule.
D) Substances that, when mixed with an antigen and injected with it, enhance the immunogenicity of that antigen.
Which of the following hypersensitivity reaction type also known as Immune-Complex Mediated Hypersensitivity reaction?
A) Type I
B) Type II
C) Type III
D) Type IV
E) Type V
C) Type III
(Mikrobiyoloji PRATIK) Aşağıdaki serolojik yöntemlerden hangisinde değerlendirme ortama katılan substrattaki renk değişimine göre yapılır? (Microbiology practice) Which of the following serological method is evaluated changing color in microwell after substrate addition?
A) Nötralizasyon testi/ Neutralisation test
B) Nefelometrik yöntem/Nephelometric method
C) Indirekt immunfloresan antikor/ Indirect Immunofluorescence test
D) ELISA/ELISA
E) Radioimmunoassay / Radioimmunoassay
D) ELISA/ELISA
