Kızıltunç Flashcards
Which of the following substances do comprise with renal glutamine metabolism?
A) Glutamate-butiric acid-ammonia
B) Ammonium ion-glutamate-a-ketoglutarate
C) Bicarbonate-glucose-CO2
D) Valine-leucine-isoleucine
E) Lactic acid-butiric acid-ammonium ion
B) Ammonium ion-glutamate-a-ketoglutarate
Which of the following reaction is source of ammonia?
A) Synthesis of glutamate
B) Synthesis of glutamine
C) Synthesis of urea
D) Excretion ammonium ion
E) Purine deamination
E) Purine deamination
Which two aa are converted to oxaloacetate?
A) Glutamine-glutamate
B) Asparagine-aspartate
C) Serine-glycine
D) Alanine-glutamine
E) Proline-threonine
B) Asparagine-aspartate
Which of the following aa carbon skeleton does convert only succinyl CoA?
A) Valine
B) Isoleucine
C) Leucine
D) Glutamate
E) Glutamine
A) Valine
Which of the following molecule is not a cofactor in aa metabolism?
A) SAM
B) tetrahydrofolate
C) blotine
D) PLP
E) GABA
E) GABA
PRACTICE Which of the following biochemistry test is not evaluated in core biochemical tests?
A) Phosphate
B) Urea
C) Amylase
D) Bicarbonate
E) Trace elements
E) Trace elements
Which of the following aa is not source for a-ketoglutarate?
A) Glutamine
B) Histidine
C) Proline
D) Arginine
E) Tyrosine
E) Tyrosine
The tubular protons are buffered with which?
A) Urea-aa-sugars
B) Creatinine-glutamine-alanine
C) Uric acid-urea-clor
D) Bicarbonate-ammonia-phosphate
E) Ammonium ion-water-urea
D) Bicarbonate-ammonia-phosphate
Thioredoxin is involved in the :
A) Conversation of AMP to ATP
B) Conversation of dUMP to dTMP
C) Conversation of a ribonucleotide to a deoxyribonucleotide
D) Inhibition of xanthine oxidase as a treatment for gout
E) Degradation of nucleoprotein
C) Conversation of a ribonucleotide to a deoxyribonucleotide
Which antibiotic does cause premature rmination synthesis?
A) Tetracycline
B) Streptomycin
C) Puromycin
D) Erythromycin
E) Chloramphenicol
C) Puromycin
PRACTICE:Which of the following biochemistry test is not evaluated in specialized tests?
A) Drugs
B) DNA analyses
C) Vitamins
D) Glucose
E) Hormones
D) Glucose
Purine and pyrimidine synthesis share several common precursors except………:
A) CO2
B) Asp
C) Gin
D) Gly
E) Folic acid analog
D) Gly
An example of a transamination is
A) Glutamate = butiric acid +ammonia
B) Glutamate=a-ketoglutarate +ammonia
C) Aspartate+glutamine = glutamate+oxaloacetate
D) Aspartate+ a-ketoglutarate= glutamate+oxaloacetate
E) Alanine+glutamine = pyruvate+glutamate
D) Aspartate+ a-ketoglutarate= glutamate+oxaloacetate
Which of the following aa is considered as both ketogenic and glucogenic?
A) Serine
B) Valin
C) Tyrosine
D) Alanin
E) Arginine
C) Tyrosine
In intestinal epithelial cell which molecule does not see glutamate conversion?
A) alpha-KG
B) Ammonium ion
C) Citrulline
D) Glutamine
E) Ornithine
D) Glutamine
PRACTIC: Which is not a urine collection style?
A) Early morning urine
B) 24 h urine
C) Post prandial urine
D) First prandial urine
E) Spot urine
D) First prandial urine
Administration of methotrexate would inhibit:
1-de novo synthesis of UMP
2-conversation of DUMP to dTMP
3-conversation of IMP to GMP
4-de novo synthesis of IMP
A) 2 and 4
B) All of them
C) Only 4
D) 1 and 3
E) 1,2 and 3
A) 2 and 4
During the fasting state, which aa is released by gut, skeletal muscle and kidney for glucose synthesis at the same time?
A) Glutamine
B) Valin
C) Tyrosine
D) Alanine
E) Aspartate
D) Alanine
With Transamination of pyruvate forms With transamination of 3-phosphoglycerate forms…….
A) Glutamine-alanine
B) Oxaloacetate-asparagine
C) a-ketoglutarate-aspartate
D) Alanine-serine
E) Acetyl CoA-lactate
D) Alanine-serine
Which of the following has no function glycosylation of proteins?
A) Asn amino acid
B) Cytosol
C) Dolichol phosphate
D) Mannose
E) Golgi complex
E) Golgi complex
What is GABA?
A) gliseraldehyde
B) glutathione amino butyric acid
C) glutamine butyric acid
D) gamma amino butyric acid
E) glutamate branched acid
D) gamma amino butyric acid
Thioredoxin is related to the :
A) Conversation of AMP to ATP
B) Conversation of dUMP to dTMP
C) Conversation of a ribonucleotide to a deoxyribonucleotide
D) Inhibition of xanthine oxidase as a treatment for gout
E) Degradation of nucleoprotein
C) Conversation of a ribonucleotide to a deoxyribonucleotide
All of ………… use in starvation as energy source.
A) Ketone bodies
B) Catecholamines
C) Vanilmandelic acid
D) Urea
E) Uric acid
A) Ketone bodies
Methotrexate is a inhibitor for step ……… and ……….
1-de nove synthesis of UMP
2-conversation of dUMP to dTMP
3-conversation of IMP to GMP
4-de nova synthesis of IMP
A) 2 and 4
B) All four
C) Only 4
D) 1 and 3
E) 1,2 and 3
A) 2 and 4
Trypsinogen is deaved by…………… to typsin
A) Chymotrypsinogen
B) Enteropeptidase
C) Proelastase
D) Procarboxypeptidase
E) Pepsin
B) Enteropeptidase
Which of the following is not the storage forms of energy in the body?
A) Glycogen
B) Free glucose
C) Triacylglycerol
D) Protein
E) Glycerol
E) Glycerol
……………………. serves as a nitrogen transporter from brain to the liver.
A) Glutamine
B) Serin
C) Valin
D) Leucine
E) Metionine
A) Glutamine
Which one is both nonessential and glucogenic and ketogenic?
A) Histidine
B) Aspartate
C) Tyrosine
D) Leucine
E) Lysine
C) Tyrosine
Which tissue does use branched chain amino acids as energy resources?
A) Liver
B) Kidney
C) Muscle
D) Gut
E) Brain
E) Brain
………………. does not undergo transamination.
A) Histdine
B) Aspartate
C) Tyrosine
D) Alanin
E) Lysine
E) Lysine
Practice:Which of the following is the principal nitrogenous product in human?
A) Urea
B) Ammonium lon
C) Creatinine
D) Uric acid
E) glucose
A) Urea
Which of the following does cause to premature
termination proteine synthesis?
A) Streptomycin
B) Puromycin
C)Tetracycline
D) Erythromycin
E) Chloramphenicol
B) Puromycin
A deficiency in …………….…..results in the disease phenylketonuria
A) Phenylalanine hydroxylase
B) Alfa keto glutarate dehydrogenase
C) Alanin aming transferase
D) Tyrosinase
E) Arginase
A) Phenylalanine hydroxylase
Which one is toxio agent in body?
A) Ammonia
B) Polatium
C) Sodium
D) Selenium
E) Phosphorus
A) Ammonia
Where does glucose-alanine cycle take place?
A) Liver-muscle
B) Liver-brain
C) Brain-muscle
D) Kidney-brain
E) Thyroid-kidney
A) Liver-muscle
Which one is a transamination reaction?
A) Glutamate = butiric acid +ammonia
B) Glutamate=a-ketoglutarate +ammonia
C) Aspartate+glutamine = glutamate+oxaloacetate
D) Aspartate+ a-ketoglutarate= glutamate+oxaloacetate
E) Alanine+glutamine = pyruvate+glutamate
D) Aspartate+ a-ketoglutarate= glutamate+oxaloacetate
Besides being the principal component of teeth and skeleton, calcium is not essential for
a) secretion
b) contraction
c) signal transduction pathway
d) coagulation
e) senthetic work
e) senthetic work
The existence of porphyrin precursor in urine is detected by chemical method like Ehrlich’s reagent or UV fluorescence technique.
The patient’s urine turns to the colour port wine on standing in ………….. diseases.
a) Variegate porphyria
b) Plumboporphyria
c) Erythropoetic protoporphyria
d) Porphyria cutanea tarda
e) Acute intermittent porphyria
e) Acute intermittent porphyria
Genetic defect of amino acids catabolism causes to inheritable human diseases in the cell. Which enzyme is deficient for tyrosinemia Type I disease in the blod?
a) Tyrosine aminotransferase
b) p-hydroxyphenylpyruvate dioxygenase
c) Fumarylacetoacetase
d) Maleylacetoacetate isomerase
e) Homogentisate 1.2-dioxygenase
c) Fumarylacetoacetase
Basic metabolic rate depends on body composition. Also, organs and tissue have various amount metabolic rate. Kidneys organ metabolic rate is higher than the adipose tissue. Because,
a) It has glutamin buffer system
b) It can synthesis urine
c) It contains high level ATPase enzyme
d) it has glycogen depositions
e) It can synthesis water
c) It contains high level ATPase enzyme