Kidneys Flashcards
Where is the macula densa located?
Distal convoluted tubule
What is the macula dens a sensitive to?
sodium concentration
When the macula densa detects a decrease in sodium it interprets it as what?
decreased blood pressure
In response to decreased sodium in blood, the macula dens a fires onto which structure, causing vasodilation?
Afferent arteriole
The macula densa causes vasoconstriction of the afferent arterioles in response to low sodium in the blood.
False; causes vasodilation
When afferent arteriole dilates, what is stretched to release renin?
Juxtaglomerular cells
Juxta glomerular cells wrap around the afferent
arteriole.
True
Renin combines with angiotensin goen to form what?
Angiotensin l
Angiotensin I becomes Angiotensin II by what?
ACE converting enzyme in the lungs
Where is Angiotensinogen made?
Liver
What is the most powerful vasoconstrictor know to mankind?
Angiotensin ll
Angiotensin II has its greatest effect on which arteriole?
efferent arteriole
What is the effect of Angiotensin 11 on the efferent arteriole
vasoconstriction
What kind of blood fluid volume control involves opening up the artery coming into the glomerulus and closing off the artery leaving the glomerulus to mechanically increase blood pressure?
Physical blood fluid volume control
Angiotensin II goes where to secrete aldosterone?
Zona glomerulosa of the adrenal cortex
Aldosterone affects what area of the nephron?
distal convoluted tubules
What is the primary action of aldosterone?
saving sodium
What is the secondary action of aldosterone?
excreting potassium
In hormonal control of blood fluid volume, what picks when sodium levels rise in the blood?
supraoptic nucleus of the hypothalamus
What is the action of the supraoptic nucleus of the hypothalamus in response to a rise of sodium levels in the blood?
release of ADH/Vasopressin
ADH has its greatest effect on which part of the nephron?
collecting ducts
What effect does ADH have on the collecting ducts?
makes them permeable to water (normally impermeable)
As water leaks out of collecting ducts in response to ADH, what kind of pressure of the peri tubular capillaries picks it up?
oncotic pressure
What happens in response to water reabsorption due to ADH?
water is returned to the blood to dilute sodium concentration, shutting off ADH
What is the effect of angiotensin Il on the heart?
Increases: Blood flow to heart, preload and cardiac output, and BP
In urine production, the fluid in the collecting ducts will enter the renal pyramids through what structure?
papillae
What is the correct passage of urine leaving collecting ducts?
papilla → minor calyx → major calyx → renal pelvis → ureter → bladder
Which portion of the bladder do the ureters empty into?
posterior bladder (trigone)
What portion of the bladder is anterior to the psoas major?
posterior bladder (trigone)
Urine production result from what 3 processes?
glomerular filtration, tubular reabsorption,
tubular secretion
The male urethra is broken up into how many segments?
4
Which segment of the male urethra is known as
the membranous urethra?
segment 3
What does the membranous urethra pass through?
the urogenital diaphragm, which is in the deep perineal pouch
What condition describes when the penile urethra comes out on top of the penis?
Epispadias
What condition describes when the penile urethra comes out the bottom of the penis?
Hypospadias
What is Peyronies Disease?
curvature of the penis due to scar tissue
What is the most common cause of Peyronies Disease?
Surgery
What part of the pen is is responsible for erection?
Corpus cavernosa
Which muscle voids the bladder?
Detrusor muscle
Except for Nat, everything is absorbed in which portion of the nephron?
proximal convoluted tubule
How many renal pyramids are in each kidney?
8- 12/Kidney
Which part of the renal pyramids includes the nephron, PCT, DCT, and the Glomerulus?
Cortex
Which part of the renal pyramids includes the Loop of Henle and collecting ducts?
Medulla
What are the invaginations between renal pyramids?
renal columns
What are foot-like processes in the kidneys called?
Podocytes
Where are podocytes located and for what function?
Bowman’s capsule for filtration