KHAN Unit 12: Behavior Flashcards

1
Q

What is the brainstem divided into? How does it connect into the other parts of the “old brain”?

A

midbrain
pons
medulla

controls HR, breathing, crossover of nerves

reticular formation: extends up into the thalamus, filters signals, arousal

thalamus: relay station

cerebellum: coordinate voluntary movement, affected by alcohol
1) motor plan (which muscles, what duration)
2) position sense information
3) feedback to cerebrum

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2
Q

What are the four lobes of the brain?

A

frontal: prefrontal cortex (executive function), motor cortex, Broca’s Area

parietal: somatosensory cortex, spatial processing (orientation)

occipital: vision, “striate cortex”

temporal: auditory processing, Wernicke’s Area

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3
Q

Compare the hemispheres of the brain.

A

contralateral control: L brain controls R body except smell

dominant hemisphere: left hemisphere for right handed people; language, (Broca’s/Wernicke’s), analytic (logic, math)

non-dominant: emotional tone of language, creativity, music

communicate via corpus callosum

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4
Q

What is the peripheral nervous system made of?

A

Nerves: contain axons of neurons
- cranial: exit skull (12 pairs)
- spinal: exit spinal cord (31 pairs)

Ganglia: contain soma (cell body) of neurons

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5
Q

What is a motor unit?

A

lower motor neuron + all the skeletal muscle cells it innervates at the NMJ

  • large muscles normally have large motor units
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6
Q

What happens with abnormality of motor units?

A

weakness
LMN signs = atrophy, fasciculations (twitches), hypotonia (decrease in tone, floppy during relax), hyporeflexia (decrease in muscle stretch reflex)

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7
Q

What is the muscle stretch reflex?

A

hit patella tendon, stretches quad muscles, muscle spindles stretch, somatosensory neurons carry signal to spinal cord and releases excitatory NT, efferent LMN releases excitatory NT in the muscle, inhibits LMN to hamstring + relaxes, quad muscle contracts

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8
Q

What are the senses of somatosensation?

A

position, vibration, fine touch: mechanoreceptors; thick myelin sheath, large diameter axon –> fast AP

pain, temperature: nociceptors, thermoreceptors; bare nerve endings; small diameter axon, thin myelin sheath –> slow AP

both of these nerves cross over in the cerebrum

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9
Q

What is grey and white matter?

A

grey: neuron somas

white: myelinated axons

spinal cord: grey matter inside, white matter outside

brain:
gray matter outside = cortex, gray matter deep inside = nuclei –> BASAL GANGLIA (motor), THALAMUS (relay), HYPOTHALAMUS (endocrine)
white matter inside (tracts: corpus callosum)

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10
Q

Lower motor neurons vs. upper motor neurons

A

control skeletal muscle cells from spinal cord vs. control LMN from the cortex (higher level control)

corticospinal tract = collection of axons that travel down from one side of the brain to the other side of the spinal cord
- right controls left
- motor functions

corticobulbar tract = UMN axons innervate LMN in the brainstem (cranial nerve nuclei)
- can cross or be same side
- face, head, neck movements

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11
Q

Upper motor neuron dysfunction signs?

A

hyperreflexia: increase in MSR (lack of inhibition)
clonus: rhythmic contraction of antagonist muscles
hypertonia: increased tone of skeletal muscles
extensor plantar response: scrape the end of foot, toes goes up instead of down

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12
Q

Most common NT.

A

Glutamate: +
- reticular activating system
GABA: -, brain
Glycine: -, spinal cord
Acetylcholine:
Histamine: hypothalamus
Norepinephrine:
Serotonin:
Dopamine: substantia nigra to striatum, hypothalamus to pituitary

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13
Q

Methods for lesion studies.

A
  1. tissue removal
  2. radio frequency
  3. neurochemical lesions
  4. cortical cooling (reversible)
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14
Q

Ways to study the brain.

A
  1. CT scans: X-rays
  2. MRI: detailed structure
  3. EEG: electrical activity
  4. MEG: magnetic fields (SQUIDS)
  5. fMRI: oxygenated blood + structure
  6. PET: inject radioactive substance
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15
Q

What is behavior?

A

Coordinated response to the environment (hormones)

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16
Q

What is the process of fertilization?

A
  1. sperm binding through zona pellucida
  2. acrosome reaction digests zona pellucida
  3. cortical reaction (egg enzymes block polyspermy)
  4. genetic transfer: DNA fuses to form diploid set of chromosomes
17
Q

Embryogenesis steps.

A

Following fusion of sperm and egg to form zygote
1. Cleavage (division)
2. Blastulation: compaction, inner cell mass + cavity
- apposition + adhesion to endometrium
3. Gastrulation: formation of endoderm, mesoderm, and ectoderm from the ICM
4. Neurulation: formation of neural tube from ectoderm (CNS)
5. Organogenesis

18
Q

What arises from each germ layer?

A

endoderm: digestive + respiratory
- GI, liver, pancreas, lining of lungs, thyroid

mesoderm: skeletal, muscular, circulatory, excretory, reproductive
- muscles, bones, heart, blood vessels, kidneys, ureters, gonads, reproductive ducts

ectoderm: skin, hair, eyes, nails, teeth, nervous system

19
Q

Steps of Gestation.

A

0 weeks: Last menstrual period
2 week: Fertilization occurs
10 weeks: Fetal development: embryogenesis + organogenesis
24 weeks: 50% chance survival
37-42 weeks = full term

20
Q

Major motor milestones.

A

2-4 months: lift head
2-5 months: roll over
5-8 months: sit up
5-10 months: stand
6-11 months: pull up into standing
7-12 months: crawl
7-13 months: walk while holding onto things
10-14 months: stand up on own
11-15 months: walk alone

gross motor skills before fine motor, head to toe development

21
Q

Primitive reflexes

A

Permanent reflex: Breathing reflex, eye blink reflex, pupillary reflex, swallowing reflex

Neonatal reflexes
- rooting: stroke cheek, turn face towards stimulus
- Babinski: bottom of foot touched, toes fan out
- Moro: loud noise, arms out then back in quickly
- tonic neck: head turned to side, arm extends and other bends
- Gallant: moves towards side of back that is stroked
- Palmer grasp: close objects into palm
- Sucking: mouth
- stepping reflex: like trying to walk
- swimming: move arms and legs around, hold breath

22
Q

When does puberty start for males and females?

A

males: first ejaculation, 14
- primary sex characteristics: testes
- secondary SC: voice, body hair, growth spurt

females: first menstrual cycle, 12-13
- PSC: ovaries
SSC: boobs, hips, hair

23
Q

What are the brain changes during adolescence?

A

Specific
- prefrontal cortex: higher order cognition, regulate emotions
- limbic system: amygdala (emotions), hypothalamus (endocrine)
- corpus callosum: connection between hemispheres (learning second language)

Global
- increase myelination
- increase synaptic pruning: “use it or lose it”