Kety Flashcards

1
Q

what was the aim?

A

to see if there’s a genetic basis for schizophrenia

to see if there’s a higher schizophrenia-related illness among biological relatives than adoptive relatives

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2
Q

what was the IV?

A

schizophrenia sufferers and a control group with no history of mental illness

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3
Q

what was the DV?

A

the prevalence of schizophrenia-related illness among family members

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4
Q

what was the sample/ppts?

A

34 schizophrenic patients aged 20-43

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5
Q

what was the procedure?

A

1-Kety used Danish family records to locate adoptive and biological relatives of all ppts
2-tracked down relatives and used mental health register to assess mental status
3-panel of psychiatrists used medical records to diagnose family members-blind test-didn’t know if records were from bio or adop relative
4-diagnoses made-identities revealed and assigned to adoptive group (IA CA) or bio group(IB CB)
-psychiatrists diagnosed family based on medical records and classified them as Schz or not

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6
Q

what was the results?

A
  • research found more signs of schz spectrum disorder in index ppts’ bio family than adop family
  • of 150 bio relatives of index cases- 13 had a diagnosis of schz,uncertain schz or inadequate personality
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7
Q

what was the conclusions?

A
  • genetic component to schz

- schz adoptees more likely to have schz in bio fam than adop fam

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8
Q

what were the controls?

A

33 mentally healthy controls selected from Danish Adoption Registry-matched with schz patients on age,gender,age at which they were adopted,social class of adop family

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9
Q

How many mz twins were there?

A

2

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10
Q

where were the ppts taken from?

A

Danish Adoption Register in Copenhagen

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11
Q

how many relatived did they track down?

A

463

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12
Q

how many psychiatrists were on the panel?

A

4

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13
Q

how many cases were dropped due to not reaching a conclusion?

A

4

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14
Q

GENERALSIABILITY

A

+large sample
+covers range of ages-teens to men and women in 40s
+men and women
-ethnocentric-same location and culture-not representatives to wider population

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15
Q

RELIABILITY

A

+reliable procedure-replicated in 1975.1978,1994

+inter-rater reliability (4 psychiatrists)

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16
Q

APPLICABILITY

A

+could help diagnose schz earlier

-results could scaremonger rather than help

17
Q

VALIDITY

A

-‘schizophrenia spectrum’ broad category placing people with different illnesses in the category-less valid

18
Q

ETHICS

A

+didn’t need consent to access records-not against law

  • ethical issues as many ppts didn’t know their records were accessed
  • sensitive topic creating potential lack of ppt protection from harm