KEL Flashcards

1
Q

Gene

A

KEL: Chromosome 7
XK: X locus

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2
Q

Ku

A

Present when Kell glycoprotein is present, universal

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3
Q

Km

A

Product of interaction between Kell and Kx

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4
Q

Ko

A
No Kell glycoprotein
Kx+s
Km-
Ku-
Can make anti-Ku
Morphologically and functionally normal
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5
Q

McLeod

A
Kx-
Km-
Ku+w
Markedly reduced Kell glycoprotein
Compensated hemolytic state
Males with neurological and muscular abnormalities
Increased CPK enzyme levels
With CGD can make anti-Kx and anti-Km
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