FY Flashcards

1
Q

Gene

A

Chromosome 1, syntenic to RH

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2
Q

Gene product

A

DARC

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3
Q

ISBT

A

ISBT 008

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4
Q

Biochemistry

A

Multipass

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5
Q

Genetic variation

A

SNP at 125: Fya/Fyb
GATA mutation: Fynull
SNP in FY*02: Fyx

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6
Q

DARC

A

Duffy antigen receptor for chemokines

Scavenger to remove unwanted chemokines

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7
Q

Duffy and Malaria

A

Fy(a-b-) resistant to binding with P. Vivax

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