Kawasaki's disease

Question 1

What is kawasaki’s disease?

Answer 1

A type of systemic vasculitis most commonly seen in children

Question 2

Highest age of incidence

Answer 2

1. 6 months to 4 years

2. Peaks at the end of 1 year

Question 3

What is the criteria for diagnosis? (w/o naming symptoms)

Answer 3

4/5 major finding on a background of fever for 5 days

Question 4

6 major symptoms of Kawasaki’s

Answer 4

1. Fever > 5 days
2. Eoedema
3. Erythematous rash
4. Lymphadenopathy - cervical lymphnodes
5. Mucous membrane involvement - bright red cracked lips
6. Conjunctivities

Question 5

What is characteristic about the fever?

Answer 5

Resistant to antipyretics

Question 6

Describe the rash in kawasaki - 2

Answer 6

1. Polymorphic and diffuse rash over large portions

2. Red palms and soles of feet which peels

Question 7

Treatment - 2

Answer 7

1. First 10 days - IV immunoglobulins

2. High dose asprin - to reduce platelet count and inflammation

Question 8

Investigations for Kawasaki (3)

Answer 8

1. Inflammatory markers - high CRP and ESR
2. Platelets rise
3. Echo - shows narrowing of blood vessels

Question 9

Major complications

Answer 9

Coronary artery aneurysms