JVD 2020 Biological Behavior of Canine Acanthomatous Ameloblastoma Assessed With Computed Tomography and Histopathology: A Comparative Study

Question 1

In JVD 2020 article

Biological Behavior of Canine Acanthomatous Ameloblastoma Assessed With Computed Tomography and Histopathology: A Comparative Study
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Stephanie Goldschmidt, Cynthia Bell

What was the primary aim of this study?

Answer 1

To determine if variations (grades) of CAA can be identified based on both histological and diagnostic imaging indices

Question 2

In JVD 2020 article

Biological Behavior of Canine Acanthomatous Ameloblastoma Assessed With Computed Tomography and Histopathology: A Comparative Study
Show all authors
Stephanie Goldschmidt, Cynthia Bell

Did the analysis identify a correlation between computed tomographic and histological appearance of the tumor?.

Answer 2

Very little correlation between computed tomographic and histological appearance of the tumor

Question 3

In JVD 2020 article

Biological Behavior of Canine Acanthomatous Ameloblastoma Assessed With Computed Tomography and Histopathology: A Comparative Study
Show all authors
Stephanie Goldschmidt, Cynthia Bell

What where the 3 consistent findings on diagnostic imagine of the CAA tumors?

Answer 3

The only consistent diagnostic imaging findings included the presence of alveolar bone lysis (100%), positive contrast enhancement (93%), and presence of cortical bone thinning (78%)

Question 4

In JVD 2020 article

Biological Behavior of Canine Acanthomatous Ameloblastoma Assessed With Computed Tomography and Histopathology: A Comparative Study
Show all authors
Stephanie Goldschmidt, Cynthia Bell

What % of tumors were intraosseous and what were extra osseous?

Answer 4

47% extraosseous and 53% intraosseous

Question 5

In JVD 2020 article

Biological Behavior of Canine Acanthomatous Ameloblastoma Assessed With Computed Tomography and Histopathology: A Comparative Study
Show all authors
Stephanie Goldschmidt, Cynthia Bell

Which location of CAA was associated with a more aggressive biological behavior?

Answer 5

Predominantly Intraosseous location

Question 6

In JVD 2020 article

Biological Behavior of Canine Acanthomatous Ameloblastoma Assessed With Computed Tomography and Histopathology: A Comparative Study
Show all authors
Stephanie Goldschmidt, Cynthia Bell

Were more drastic changes on imaging correlated with more aggressive Histopathologic findings?

Answer 6

NO

Despite the variability noted on diagnostic imaging of CAA, especially regarding the severity of lytic extension associated with the tumor, there was little variability on histopathology.

Question 7

What are the differences between CAA and conventional ameloblastoma on imaging?

Answer 7

Conventional ameloblastoma tends to have highly consistent imaging findings and are almost always consistent with a locular/cystic intraosseous mass, which does not tend to aggressively infiltrate adjacent tissue past the margin of the cyst.

Within the present study, CAA was rarely associated with cystic structures (11%) and presented with equal frequency in a predominantly extraosseous or intraosseous location. Furthermore, CAA had highly variable computed tomographic findings especially in regard to severity of bone lysis, with the level of invasion dictated in part by its predominant location