JVD 2019 #2 Validation of Regional LN Excisional Bx for Staging MXfacial Malignant Neoplasms in 97 dogs & 10 cats (2006-2016), Odenweller; Mark Smith, Kendall Taney Flashcards
How many cases had metastasis to one or more regional LNs based on histopath?
14% of 107 cases
Of those cases with metastasis to region LNs (14% of 107) how many affected the mandibular lymphocentrum? How many ONLY the MN lymphocentrum?
73% affected the MN lymphocentrum
72% only affected the MN lymphocentrum
Of those cases with metastasis to region LNs (14% of 107) how many affected the mandibular and medial retropharyngeal lymphocentrums? How many had had all 3 (MN, Med retro ph., & parotid)?
- 2% affected the mandibular and medial retropharyngeal lymphocentrums
- 1% affected all 3 (parotid, med retro & MN)
Why to sample multiple lymphocentrums?
The parotid, mandibular, and medial retropharyngeal
lymphocentrums
each receive afferent
lymphatics from particular regions, with some areas of overlap, including the possibility of
contralateral metastasis via lymphatic anastomotic connections.
What were the main differences between this study and the 2002 JVD LN staging of Oral & MXfacial neoplasms in 31 dogs and cats by Herring (and mark smith)
2019- substantially lower incidence of regional metastatic disease = 14% compared to previous 35.5%(2002)
2019- 26% of 15 cases with + lymph nodes had NO evidence of mets in MN lymphocentrum versus 56% (54% HAD mets to MN lymph nodes in 2002)
In Ku “Cytological-histological concordance in the diagnosis of neoplasia in canine and feline lymphnodes: a retrospective study of 367 cases.” In Vet Comp Oncol 2017- what was the % accuracy of FNA in assessing metastasis?
FNA to be less reliable in assessing metastasis, reporting 77.2% accuracy in dogs and cats.
2015 J Small Anim Pract- Amores-Fuster “The diagnostic utility of LN cytology samples in dogs and cats.” found FNA able to assess metastasis in what %
72.8% dogs and 85.9% cats
