Junctions And Tissues Flashcards
What are the 3 types of junctions between cell types?
Adhering
Impermeable
Communicating
What are features of adhering junctions?
Mechanically held together
Eg desmosomes containing plaque
Common
What do belt desmosomes do?
Form continuous band around the cell, common in epithelial cells where they are associated with actin filaments
What do spot desmosomes do?
Spot weld cells together, and are attached on inside of the cell to keratin filaments
What do hemi desmosome do?
Attach the base of the cell to basal lamina
What are the features of impermeable junctions?
Prevent the passage of molecules between cells
Eg tight junctions
No molecules between cells
In invertebrates, what junctions form the same function as tight junctions?
Septate junctions
What are the features of communicating junctions?
Allow passage of small molecules from one cell to another Eg gap Common Connexins form the gap 1.5nm gap
How is the permeability of gap junctions changed?
Decreased intercellular pH
Increased intracellular calcium
What happens to gap junction during cardiac disease?
They are reduced in numbers or changed in distribution
What are the 4 main categories of tissue?
Epithelial
Connective
Muscle
Nervous
What are the features of epithelial tissue?
Tightly packed cells
Fastened together via desmosome junction and tight junctions
Acts as barrier and protects against mechanical injury
Secretory functions
What are the features of connective tissue?
Extra cellular matrix
Dense or loose
Blood and adipose
What are examples of dense connective tissue?
Cartilage, bone, tendon, ligament tissue
What is dense connective tissue composed of?
Fibrous proteins
Glyosaminoglycans attaches good protein core