Cytoskeleton Flashcards

1
Q

Describe microfilaments

A

7mn
Composed of two actin filaments twisted
Muscle contraction

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2
Q

Describe intermediate filaments

A

8-10nm
Diverse group of proteins
Maintain position of organelles and shape of cell

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3
Q

Describe microtubules

A

Hollow rods
25nm
Constructed of globular proteins Tubulins

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4
Q

Why is the cytoskeleton important?

A

Its in every cell and critical to normal embryonic development

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5
Q

Abnormalities in the cytoskeleton result in what?

A

Myriad of diseases affecting every tissue in the body

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6
Q

Where are microfilaments found?

A

All eukaryotic cells

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7
Q

What are microfilaments used for?

A

Contraction of muscles where they interact with myosin filaments

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8
Q

What holds together the two lobes of the actin monomer?

A

ATP

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9
Q

What does G actin assemble into?

A

Helical f actin polymers

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10
Q

What do toxins such as phalloidin do to F actin?

A

Prevent disassembly- can be used to stain actin

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11
Q

Where is phalloidin found?

A

Death cap mushrooms

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