Cytoskeleton Flashcards
Describe microfilaments
7mn
Composed of two actin filaments twisted
Muscle contraction
Describe intermediate filaments
8-10nm
Diverse group of proteins
Maintain position of organelles and shape of cell
Describe microtubules
Hollow rods
25nm
Constructed of globular proteins Tubulins
Why is the cytoskeleton important?
Its in every cell and critical to normal embryonic development
Abnormalities in the cytoskeleton result in what?
Myriad of diseases affecting every tissue in the body
Where are microfilaments found?
All eukaryotic cells
What are microfilaments used for?
Contraction of muscles where they interact with myosin filaments
What holds together the two lobes of the actin monomer?
ATP
What does G actin assemble into?
Helical f actin polymers
What do toxins such as phalloidin do to F actin?
Prevent disassembly- can be used to stain actin
Where is phalloidin found?
Death cap mushrooms