Joint & Connective Tissue Flashcards

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1
Q

assessment for joint/connective tissue problems include

A

gait, posture, functional assessment (observe activities like transfer to chair, dressing/ADL)

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2
Q

ESR is

A

rate of sedimentation of RBC, inflammation causes clumping of RBC so higher ESR level an indication of inflammation

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3
Q

antiarthritic drugs: 3 categories

A
  1. NSAIDs, non-steroidal anti inflammatory drugs including aspirin
  2. DMARDs disease modifying anti rheumatic drugs
  3. glucocorticoids - adrenal corticosteroids
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4
Q

inflammatory connective tissue diseases: 3

A
  1. RA
  2. SLE (systemic lupus erythematosus
  3. Scleroderma
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5
Q

serum lab tests:

A
  1. ESR
  2. Uric Acid
  3. ANA (antinuclear antibody)
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6
Q

3 goals of rheumatic disease

A
  1. suppress inflammation and the autoimmune response
  2. control pain
  3. maintain or improve joint mobility
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7
Q

osteoarthritis definition

A

chronic, causes cartilage deterioration in synovial joints and vertebrae.

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8
Q

osteoarthritis affects

A

weight bearing joints: hips and knees

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9
Q

osteoarthritis pain: when?

A

worse with activity, better with rest, not usually at night

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10
Q

crepitus during ROM activity

A

sign of OA

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11
Q

herberden: definition

A

enlarged upper joints of the fingers/DIP joints

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12
Q

bouchard: definition

A

enlarged lower joints of the fingers/PIP joints

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13
Q

radiographic/X Rays show

A

osteophytes - (bone spur) bony growth at the end of a bone

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14
Q

MRI show

A

cartilage, synovium and bone

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15
Q

osteoarthritis interventions:

A

no treatment to stop degeneration of joints so

  1. educate
  2. reduce pain and inflammation
  3. maintain function
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16
Q

NSAID risk

A

GI complications

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17
Q

arthroplasty and osteoarthritis:

A

surgical repair of the joint

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18
Q

intra-articular injections

A

hyaluronic acid - acts as synovial fluid in joint space

corticosteroids - methylprednisolone

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19
Q

hot or cold treatment timing

A

20 minutes on/off

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20
Q

gout: definition

A

urate crystals deposited in joints, problem with purine metabolism > hyperuricemia (high uric acid in blood)

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21
Q

primary gout: definition

A

genetic, overproduction of uric acid or decreased urate excretion in the kidney

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22
Q

secondary gout definition

A

also hyperuricemia, diabetic ketoacidosis (DKA), starvation

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23
Q

tophi: definition

A

urate/uric acid crystals deposited in peripheral areas like great toe, hands or ear.

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24
Q

acute gouty arthritis: definition

A

recurrent attacks of joint inflammation/ acute arthritis

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25
diagnostics for gout: 4
1. uric acid test, 6.8 is gout 2. 24 hour urine collection 3. x-ray 4. aspiration of fluid from inflamed joint to see crystals
26
gout ice or heat?
ice
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gout medications
chochicine (colcrys) - interfere with function of WBC so no inflammatory response
28
chochicine (colcrys) side effects
diarrhea, take with meals,
29
gout nursing interventions
1. pain mgmt - cold compression 2. hydration - avoid kidney stones 3. diet - avoid pureens (organ meat, alcohol, red meat) 4. healthy weight
30
rheumatoid arthritis unilateral?
no, affects both sides at same time
31
RA sign
morning stiffness for an hour before pain
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RA causes
1. rheumatoid factor (RF) antibodies form against IgG | 2. synovial membrane destruction leads to pannus
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RA signs
deformities of hands and feet fatigue weight loss Raynaud's
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arthrocentesis
RA diagnostic, synovial fluid analysis
35
swan neck deformity
deformed position of the finger due to RA
36
RA labs
``` RF high Anti CCP high ESR high ANA high RBC lower ```
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DMARDs
methotrexate - anti inflammatory, give with folic acid supplement, s/e aplastic anemia
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saline eye drops for
RA
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connective tissue types include
bone, blood and organs
40
ESR diagnose? evaluate treatment?
not to diagnose, evaluate
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intercritical symptoms?
no
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gout in the great toe called
podagra
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uric acid level signals gout
6.8
44
gout and kidney stones (uric acid filtered by kidneys)
purines make up 15 percent of uric acid, uric acid > gout and kidney stones
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colchicine/Colcrys timing
must be taken within 24 hours of onset of acute gout attack
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XOI (Xanthine Oxidase Inhibitors) treat
gout by blocking uric acid formation
47
XOI side effects
anti diabetes meds: hypotension, hypoglycemia
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Uricosuric treat
gout by lower/inhibit renal reabsorption of uric acid so excreted out in urine, decrease serum uric acid
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Uricosuric risk
kidney stones
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Uricosuric not to be taken with
aspirin and thiazide diuretics
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gout hydration amount and reason
2L to prevent kidney stones
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osteoarthritis level of activity
moderate
53
osteoarthritis s/s
stiff joints b/c loss of synovial fluid crepitus no inflammation worse pain bad weather
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osteoarthritis and WBC
WBC WNL b/c no systemic inflammation, just local swelling
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osteoarthritis assessment
morning stiffness: 30 minutes
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tylenol / acetaminophen
max 4000 mg/ 4g
57
osteoarthritis hot or cold
temperature treatments hot and cold
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osteoarthritis meds
COX2 Inhibitors / celecoxib / celebrex for local inflammation
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COX2 Inhibitors / celecoxib / celebrex side effects
cardiovascular problems, MI, CVA, high BP
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autoimmune local?
systemic
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systemic example
dry mucus membranes, wrist pain, cold feet
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RA unilateral
bilateral
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RA assessment
morning stiffness 1 hour
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Rheumatoid Factor RF specific to RA
no, all inflammation have high RF
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arthrocentesis fluid color
synovial fluid s/b clear, not cloudy or milky (b/c antibodies in it)
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any med that treats inflammation risk
infection b/c WBC inhibited
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Tumor Necrosis Factor (TNF) treat
RA
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Tumor Necrosis Factor (TNF) side effects
TB so manteaux test before, no live vaccines
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dairy and inflammation
can cause it
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SLE risk factors
15-40 YO, black and hispanic women,
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SLE cause
anti-DNA antibodies, blood vessels attacked/inflamed
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SLE and kidneys
lupus nephritis
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SLE and skin
rash, photosensitivity, butterfly rash,
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Scleroderma definition
connective tissue disease, hardening of the skin
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Scleroderma effects
loss of skin elasticity incl lungs, esophagus and GI tract hardening
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Scleroderma interventions
impaired swallowing and constipation
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RA s/s
bilateral joint pain, weight loss, joint deformed, tinnitus, GERD
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SLE s/s
fever, nephritis
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ANA serum test to
diagnose
80
ESR blood test to
evaluate treatment
81
pannus is
highly vascular granulation tissue
82
SLE usually linked to
Scleroderma
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Rheumatoid Arthritis (RA) vs Osteoarthritis (OA) similarities
1. RA and OA both forms of arthritis which is pain in the joints 2. both chronic 3. both
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RA vs OA type of disease
RA autoimmune | OA "wear and tear" over time, degenerative, destroys cartilage in synovial joints and vertebrae
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RA vs OA symptoms
RA joint pain, inflammation, stiffness | OA joint pain, non inflammatory, stiffness
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RA vs OA location
RA inflammation in pairs of smaller joints, both hands, both ankles, etc OA weight bearing joints (back, hip, knee)
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RA vs OA timing
RA worse in morning for at least 1 hour | OA morning for 30 minutes, gets worse with activity during day
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RA vs OA systemic symptoms
RA, systemic fatigue, weight loss, weakness | OA, localized