Diabetes Flashcards
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glucose intolerance: 2 types
- no or little production of insulin
2. tissue insensitivity to insulin
insulin: definition
hormone secreted by beta cells in pancreas
insulin controls blood glucose by regulating: 3
- production of glucose
- use of glucose
- storage of glucose
high blood glucose level: 4 steps
- glucose enters body tissues/cells
- excess glucose stored in liver as glycogen
- beta cells in pancreas stimulated to release insulin into the blood
- blood glucose level declines to a set point, stimulus for insulin release diminished
low blood glucose level: steps
- alpha cells in pancreas stimulated to release glucagon into the blood
- liver breaks down glycogen and releases glucose into blood
- blood glucose level rises to a set point and stimulus for glucagon release diminished
type 1 diabetes: definition
destruction of beta cells mean deficiency of insulin secretion
type 1 diabetes: causes
genetic and autoimmune
type 1 diabetes: insulin production
pancreas produces no insulin
type 1 diabetes: patient profile
young and thin
type 1 diabetes: prone to
ketosis
insulin primary role
help glucose enter body cells for energy source
ketones: definition
acidic byproduct of breakdown of fats in blood
diabetic ketoacidosis: steps
- hyperglycemic
- insulin not sufficiently produced to offset high blood glucose
- body uses stored fat for energy b/c can’t use glucose b/c glucose can’t enter cells w/o insulin
- ketones result of fat breakdown
- diabetic ketoacidosis is untreated ketones
diabetic ketoacidosis timing
quickly even within 24 hours
ketoacidosis diagnostics: 2
ketones in urine test
hyperglycemia
ketoacidosis: signs and symptoms: 2
- fruity breath
2. abdominal pain
type 1 diabetes: 3 “Ps” signs and symptoms
Polyuria - excessive urination
Polydipsia - thirst
Polyphagia - hunger
type 2 diabetes: signs and symptoms
3 Ps plus
- hand tingling/numbness
- slow healing wounds
- recurrent infections
type 2 diabetes: ketosis?
no
type 2 diabetes: greatest risk factor
obesity
type 2 diabetes: 3 causes
- low beta cell count
- insufficient insulin production to offset high blood glucose level
- tissue insensitivity to insulin
type 2 diabetes and insulin production
insulin is produced by either not enough to handle high blood sugar or tissue/muscle resisting glucose b/c obesity
diabetes during pregnancy called
gestational, usually resolves after birth
a cluster of conditions that occur together that increase chances of CVA, type 2 diabetes
metabolic syndrome