Coronary Artery Disease Flashcards
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CVD (cardiovascular disease) cause
atherosclerosis
atherosclerosis is
abnormal accumulation of fatty substances and lipids and fibrous tissue on arterial walls
atherosclerosis in heart
block or narrow coronary arteries which reduce blood flow to myocardium
tachycardia effect on oxygen
high, rapid HR will increase demand for oxy
3 reasons low serum oxygen supply
anemia, blood loss, low blood pressure, hypovolemia
low blood supply/ deprive heart muscle cells of oxy
myocardial ischemia - oxy demand ^ supply
myocardial ischemia reversible or chronic?
reversible but if progress to necrosis no
chest pain from myocardial ischemia
angina pectoris> low oxy> dead muscle cells>MI
MI myocardial infarction
blood clot blocks blood flow to heart
angina pectoris pain
crushing, substernal, SOB, n/v, diaphoresis, relieved by rest or nitrates
MI myocardial pain
same as angina but no relief from rest or nitrates
diabetes/hyperglycemia and CVD
diabetes>hyperlipidemia>increased platelet aggregation>altered RBC function>thrombus formation
predictable and consistent chest pain
stable angina pectoris
angina cause
obstruction/atherosclerosis of major coronary artery
nitrates/nitroglycerin action
reduce myocardial oxy demand, so ischemia and pain decreased, dilate veins and arteries, relax alveoli so increase oxy
nitrates routes
oral, transdermal, sublingual
why assess for hypotension before nitrate admin
small doses of nitro can trigger hypotension and bradycardia
nitrates prevent or treat angina?
both, nitroglycerine part of nitrates class of drugs
nitrates: 2 types
daily maintenance/prevention and acute response
sublingual nitrate administration for acute cases
sit and place under tongue, take up to 3 doses 5 minutes apart, no relief after 15 min call 911, do not drive to hospital
sublingual nitrate storage
dark brown container, expires 6 months after opening, store in neutral temperature
sublingual nitrate reversal agent/antidote
atropine - IV
nitrate transdermal admin
wear gloves when prepare and admin patch/ointment
pain relief for nitrate patient
aspirin or acetaminophen
notify HCP after nitrates if
dry mouth or blurry vision
oxygen admin for angina/chest pain when, action, result, monitor
initiate at onset of pain, inc myocardial oxy supply and decrease oxy demand, decreases chest pain and monitor Sa02
Sa02 is
oxygen saturation; measure % of hemoglobin is bound/saturated to oxygen; arterial blood measure vs Sp02 with pulse oximeter (peripheral)
cardiovascular disease: 4 diagnostics
Serum Cardiac Markers
Lipid profile
Stress test
Cardiac Catherization
serum cardiac markers are
biomarkers used to evaluate heart function