Jeopardy Review

Question 1

The VA found that more patients taking placebo to manage hypertension discontinue treatment because of side effects than those taking these medications.

Answer 1

ACEs, thiazide, calcium channel blockers

Question 2

What hypertension med should you rx if your patient has diabetes and/or renal disease AND HTN?

Answer 2

ACE or an ARB

Question 3

For HF patients with reduced ejection fraction: an ACE or an ARB, a beta blocker, an aldosterone antagonist, SGLT2 inhibitors, or an ARNI

Question 4

This non-diuretic, but commonly used antihypertensive agent is NOT one of the 4 pillars of GDMT because medication in this class do not have a proven mortality beenfit.

Answer 4

What are calcium channel blockers?

Question 5

These antihypertensive medications can cause peripheral edema via arteriolar vasodilation resulting in increasing capillary pressure.

Answer 5

What are calcium channel blockers?

Question 6

This highly effective group 3 anti-arrhythmic agents prolongs the action potential duration and the refractory period via K channel blockade. Also has calcium channel, and beta blocker properties.

Answer 6

What is amiodarone?

Question 7

These antihypertensive medications reverse peripheral edema caused by arteriolar vasodilation (calcium channel antagonists)

Answer 7

ARB

Question 8

This beta lactam antibiotic can be safely prescribed in patients having a history of a type I HSR reaction.

Answer 8

What is aztreonam?

Question 9

When compared to less than recommended doses of enalapril in patients with reduced EF, this medication improved mortality for 1 out of 36 patients, but one out of 8 will drop out due to symptomatic hypotension. THe cost benefit is around $650 per month.

Answer 9

What is Entresto?

Question 10

This longer acting agent for nodal reentry tachycardia is an alternative for patients not at risk for hypotension.

Answer 10

What is a non-DHP (diltiazem, verapamil)?

Question 11

Key questions to ask your patients who have a history of an allergic reaction to penicillin.

Answer 11

Characteristics and severity of the reaction?
What happened when it was discontinued
Has the patient taken abx similar to pencillin before or after the rxn? What happened?

Question 12

This class of medications inhibits thromboxane and can also inhibit prostacyclin synthesis

Answer 12

NSAIDs

Question 13

This anti-arrhythmic medication is also an endogenous compound, and is the first line treatment for conversion of PSVT to sinus rhythm.

Answer 13

What is adenosine?

Question 14

Control of hypertension. Maybe use of an ARB, or aldosterone antagonist, or an SGLT2 inhibitor, and maybe women with an LVEF between 45-47%.

Answer 14

What are recommended treatments for HFpEF?

Question 15

This medication prevents binding of fibrinogen and vWF to the GPIIb/IIIa receptor.

Answer 15

What is the MOA of eptifibatide or tirofiban)

Question 16

This class of medications on the distal tubule to reduce sodium resorption, basically putting patients on a low sodium diet.

Answer 16

What are thiazide diuretics?

Question 17

Use of this beta blocker adds a mortality benefit when appropriately used in patients with heart failure

Answer 17

What is metoprolol succinate or carvedilol?

Question 18

Atorvastatin and rosuvastatin classification?

Answer 18

High intensity statins

Question 19

OK to use a full dose 3rd or 4th generation cephalosporin when…

Answer 19

Patients who have a mild, non IgE mediated reaction to penicillin

Question 20

Inhibition of prostaglandin synthesis by this analgesic can result in increased synthesis of leukotrienes resulting in bronchoconstriction?

Answer 20

What is aspirin?

Question 21

This medication inhibits platelet

Question 22

This nitrate is essentially a longer acting nitroglycerin

Answer 22

What is isosorbid dinitrate?

Question 23

Non DHP CCBs acrting preferentially on nodal tissue to block the slow inward calcium channel. Used for long term control of the ventricular rate in patients with atrial fibrillation or flutter that also have asthma

Answer 23

What are verapimil or diltiazem?

Question 24

In IHD these agents decrease oxygen demand.

Answer 24

What are organic nitrates, beta blockers, and some CCBs?

Question 25

In IHD these medications increase oxygen supply.

Answer 25

What are vasodilators?