CRC Treatments Quiz

Question 1

This anti metabolite pairs with adenine (RNA) or thymine (DNA) thus blocking replication and ultimately resulting in cell death

A) Methotrexate
B) Fluorouracil
C) Doxorubicin
D) Bleomycin

Answer 1

B

Question 2

This medication enhances the activity of anti metabolite used in CRC by binding to thymidylate synthase

A) Ascorbic acid
B) Thiamine
C) Folinic acid
D) Ergocalciferol

Answer 2

C

Question 3

Capecitabine is an oral version of:

A) Cephalexin
B) Folinic acid
C) Oxaliplatin
D) Fluorouracil

Answer 3

D

Question 4

Irenotecan is a

A) The topoisomerase inhibitor used in FOLFIRI
B) False neurotransmitter
C) An antimetaboite
D) A source of folic acid

Answer 4

A

Question 5

These monoclonal antibodies are used to treat selective patients with CRC

A) Cetuximab (Erbitux) and panitumumab (Vectibix) can benefit selected patients via amplification of the efficacy of irenotecan
B) Bevacizumab (Avastin) an antiangiogenesis agent, acts as a monoclonal antibody directed against the vascular endothelial growth factor (VEGF)
C) Tarceva and Sutent are inhibitors of EGFR via tyrosine kinase
D) A and B are correct

Answer 5

D