Basic GI PCol Quiz

Question 1

Which statement about management of CDI is correct?

A) Encourage frequent use of hand sanitizers
B) Treatment includes oral metronidazole or IV vancomycin
C) Treatment includes oral metronidazole or oral vancomycin
D) Use fidaxomicin for initial treatment

Answer 1

C - Hand sanitizer does not kill C diff because it has spores so must wash hands. Vancomycin cannot cross BBB so must be taken orally for local/C diff infection. systemic infection would need IV Fidaxomicin is not first line, vanco is. Fidaxomicin also has no activity against gram-negative bacteria

Question 1

Which statement about CDI is NOT correct?

A) C difficile is a gram positive, spore forming rod
B) Primary cause of hospital associated diarrhea in US
C) Overgrowth in gut supported by antibiotic use
D) Caused by bacteroides fragilis

Answer 1

D - C. diff is a gram positive, rod shaped bacterium. Bacteroides fragilis is an obligately anaerobic, Gram-negative, rod-shaped bacterium. It is part of the normal microbiota of the human colon and is generally commensal, but can cause infection if displaced into the bloodstream or surrounding tissue following surgery, disease, or trauma.

Question 2

All of the following medications are commonly associated with constipation except?

A) Vincristine
B) Verapamil
C) Vancomycin
D) Varenicline

Answer 2

C - Drugs that commonly cause constipation:
Opioids
Anticholinergic
Tricyclic Antidepressants
Calcium channel blockers (Verapamil)
Anti-parkinson drugs
Antipsychotics
Diuretics
Antihistamines
Antacids (TUMS)
Calcium supplements
Iron supplements
NSAIDs