jaundice

Question 1

jaundice is caused by

Answer 1

raised bilirubin

Question 2

bilirubin is derived from

Answer 2

breakdown of haemoglobin in the spleen

Question 3

how is bilirubin transported

Answer 3

bound to albumin

Question 4

where is bilirubin conjugated

Answer 4

liver

Question 5

what is the bilirubin conjugated to

Answer 5

bilirubin glucuronide

Question 6

how does bilirubin leave the liver

Answer 6

excreted via the bile duct into the small intestine in bile

Question 7

what happens to conjugated bilirubin in the terminal ileum

Answer 7

converted to urobilinogen and excreted in the faeces or absorbed by kidenys and excreted

Question 8

what is urobiligen excreted in the stool as

Answer 8

stercobilinogen

Question 9

where does bilirubin become urobiligen

Answer 9

terminal ileum

Question 10

three categories of jaundice

Answer 10

Haemolytic jaundice
Congenital hyperbilirubinaemias
Cholestatic jaundice

Question 11

Cholestatic jaundice

Answer 11

failure of bile secretion by the liver or bile duct obstruction

Question 12

Haemolytic jaundice principal

Answer 12

Increased breakdown of red blood cells leads to increased production of bilirubin

Question 13

what is raised in haemolytic jaundice

Answer 13

raised serum unconjugated bilirubin

Question 14

most common congenital hyperbilirubinaemia

Answer 14

gilberts

Question 15

what does bilirubinget conjugated to

Answer 15

glucuronic acid

Question 16

what is the issue in gilberts

Answer 16

reduced enzyme for bilirubin conjugation

Question 17

gilberts treatment

Answer 17

not needed

Question 18

cholestatic jaundice ca be divided into

Answer 18

intrahepatic

extraheptaic