IBD/diverticular/toxic mega

Question 1

where does UC affect

Answer 1

colon

Question 2

where does crohns affect

Answer 2

can do whole GI tract

Question 3

smoking and IBD

Answer 3

increases chance of crohns

reduces risk of UC

Question 4

mental that may influence IBD

Answer 4

stress and depression can preceed episodes

Question 5

difference in location pattern of UC and crohns

Answer 5

crohns - skip lesions

UC - continuous

Question 6

what is cobblestone appearance

Answer 6

deep ulcers and fissures in crohns

Question 7

where is the inflammation in crohns

Answer 7

transmural

Question 8

transmural

Answer 8

across the entire wall of an organ or blood vessel

Question 9

where does UC begin

Answer 9

rectum and extends

Question 10

feature of UC lumen

Answer 10

red mucosa and bleeds easy

Question 11

where is the inflammation in UC

Answer 11

mucosal

Question 12

which IBD has a high chance of granulomas

Answer 12

crohns

Question 13

microscopic findings of UC

Answer 13

Goblet cell depletion

Crypt abscesses

Question 14

what is IBD

Answer 14

innapropriate immune response to things in the lumen

Question 15

in the IBD pathophys which cells take over

Answer 15

effector T cells predominating over regulatory T cells.

Question 16

what do the effector T cells release

Answer 16

proinflammatory cytokines

Question 17

what do the proinflmmatory cytokines do

Answer 17

promote macrophages to release TNF

Question 18

most common site for crohns

Answer 18

ileocaecal

Question 19

colon crohns symptoms

Answer 19

diarrhoea, bleeding and pain related to defecation

Question 20

UC presentation

Answer 20

diarrhoea, often containing blood and mucus

Question 21

why might you see anaemia on blood test

Answer 21

normocytic normochromic anaemia of chronic disease

or cant absorb B12

Question 22

Crampy abdominal pain relieved by defecation or wind

Answer 22

IBS

Question 23

common symptoms of IBS

Answer 23

altered bowel habit, a sensation of incomplete evacuation, abdominal bloating

Question 24

diverticular formation

Answer 24

mucosa extrude through the colonic muscular wall

Question 25

where are there weakened areas where diverticular can form

Answer 25

weakened areas near blood vessels

Question 26

cause of diverticular disease

Answer 26

low fibre diet

Question 27

diverticular symptoms

Answer 27

pain and constipation and bleeding

Question 28

what does diverticulitis present with

Answer 28

left iliac fossa pain
fever and nausea
fistula into bladder

Question 29

blood supply to colon

Answer 29

superior and inferior mesenteric arteries

Question 30

area in colon most susceptible to ischemia

Answer 30

splenic flexure

cecum

Question 31

what is toxic megacolon

Answer 31

extreme dilation of the GI tract

Question 32

what is a big risk with toxic megacolon

Answer 32

perforation