Ischemic Dermatopathies Flashcards
Key Points
Types of lesions
Differentials
Treatments
Group of vasculopathic skin diseases
Atrophied lesions with erythema, scale/crust, erosions/ulceration, pigmentary changes
Other Ddx: demodicosis, bacterial folliculitis, dermatophytosis
Most reliable symptomatic therapy: Pentoxifylline and Vitamin E
FDM
Familial Dermatomyositis
Common in Rough coated collies, Shelties
Scarring alone is of the face, distal extremeties, tail tip and other boney prominences
Lesions: erythema, alopecia, scales, crusts which progress to ulceration and erosions, secondary pyoderma on top
Can start as early as 7 - 11 weeks of age
May or may not display signs of muscle weakness
Rabies Vaccine Induced Vasculitis
Localized inflammatory or ischemic reaction to SQ admin Rabies vax
Small breed dogs common
Lesions: Atrophic, depressed, alopecic patches at vax site, older lesions may become hyperpigmented
Ddx: staph foliculitis, demodicosis, dermatophytosis, alopecia areata
Vaccine Associated Ischemic Dermatopathy
Post vaccine dermatopathy
Similar to FDM except with the original focus of alopecia (ie injection site) visible.
Affects periorificial skin or areas of boney prominences
Mild to moderate muscle atrophy
Ddx: FDM, idiopathic ischemic dermatopathy
Idiopathic Ischemic Dermatopathy
No clear temporal association with vax
Adult dogs
Atypical breed for FDM
Causal association rarely identified (rule out antigenic stimulation, food reaction)
Proliferation Thrombovascular Necrosis of Pinnae
Aka Pinnal Margin Vasculopathy
Lesions being on apical margins of pinnae
Crusting, erythema can progressed to notched ear margins
Most common in Dachshunds, Ridgebacks
Treatment: Pentoxifylline
Pentoxyfilline Dose
15 - 30 mg/kg every 8 - 12 hours
Vitamin E
Antioxidant that quenches oxygen free radicals
Constituent of sebum which is delivery cont to epidermis
200 IU small
400 IU medium
600 IU large
Q 12 hours
