Ionophores & Implants Flashcards

1
Q

What are ionophores?

A

Carboxylic antibiotics

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2
Q

T/F: Ionophores are medically important

A

False

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3
Q

Why do we love ionophores?

A

Increase efficiency of energy metabolism of ruminal bacteria

Improve nitrogen metabolism of bacteria

Retardation of digestive disorders resulting from abnormal rumen fermentation (bloat)

Basically: we put less in and they put more out! Magic!

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4
Q

What are the two commonly used ionophores?

A

Monensin (Rumensin) and Bovatec (Lasalocid)

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5
Q

T/F: Ionophores create slightly better environment for propionate producing bacteria.

A

True - increased propionate

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6
Q

What are some other side benefits of rumensin and lasalocid?

A

Decreases bloat risk by decreasing slime producing bacteria

Decreases fly pupae in feces???

Helps a lil with atypical interstitial pneumonia

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7
Q

Do ionophores work better on concentration or roughage diets?

A

Works on both!

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8
Q

Who is most sensitive to monensin?

A

Horses!

Can also be toxic to sheep and cattle if fed enough

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9
Q

Beta-agonists are ______ agents

A

Repartitioning

Per google, a repartitioning agent is “an agent which will direct substrates away from adipose tissue depots and towards muscle accretion”

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10
Q

When do producers feed beta-agonists?

A

Last 28-42d of feeding period

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11
Q

What kinda things do we use as growth promotants?

A

Hormones! - Estrogen, Testosterone, Progesterone

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12
Q

What group do we most commonly use growth implants for?

A

Feedlot cattle
Most last 90-100 days, some 200 days

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13
Q

T/F: New guidelines from the FDA say that implants can be used year-round, regardless of production stage.

A

False - implants can only be used once in each phase of calf production (unless labeled for re-implant)

  1. Cow-calf
  2. Stocker
  3. Feedlot
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14
Q

Where are growth implants administered?

A

Middle third of the ear

If the middle third of the ear has been damage, place implant on the top of the ear

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15
Q

What is the key to using growth implants?

A

Must be gaining well to begin with

Return is increased gain of 10-15%

Better return if you’re getting 15% gain on 2lbs/day compared to 15% on 0.25lbs/day

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16
Q

Mode of action of ionophores

A

Disrupt cation transport in the cell

…whatever that means

17
Q

Which ionophore is most common in feedlots?

A

Rumensin

18
Q

Which ionophores is more common in dairy heifers rations?

A

Lasalocid

19
Q

Ractopamine is an example of _______

A

Beta-agonists

20
Q

Which beta-agonist was declared illegal and can result in jail time if used?

A

Clenbuterol

21
Q

What was the bummer for DES?

A

Caused cervical cancer in daughters of women who took DES during pregnancy

22
Q

How do androgens and progesterones work to promote growth?

A

Increase nitrogen retention

Decrease degradation at the level of the muscle

23
Q

What is the most common suckling calf implant?

A

Ralgro