Ion Exchange 1 Flashcards
What is ionic balance responsible for
Maintaining cell shape & resting membrane potential
What is pH balance responsible for
Protein folding & enyzme functions within restricted pH ranges
What is nitrogen balance responsible for
Nitrogenous wastes that are converted to toxic ammonia need to be excreted as either ammonia, urea, or uric acid
What do water, ionic, pH, and nitrogen regulation all affect
Blood volume, pressure, and heart function
What are perturbing solutes
Inorganic ions, charged amino acids, ammonia that disrupt macromolecular function
What are compatible solutes
Trehalose, glycerol, glucose, and uncharged amino acids. Do not disrupt function, even at high concentrations.
What are counteracting solutes
Harmful individually, but in combination are not harmful (Urea, methylamines such as TMAO)
Can you actively transport water
NO
Water follows ___
Solute
If you move ions into the cell, water moves __
Into the cell
If you move ions out of the cell, water moves ___
Out of the cell
How much water can pass through an aquaporin in one second
1 billion water molecules
What type of cells play a role in regulating salt-water balance in animals
Epithelial cells
How do solutes move across epithelial cells
Transcellular & Paracellular transport
What are four properties of epithelial cells
- Asymmetric distribution of transporters/channels
- Junctions regulating paracellular transport
- Diversity of epithelial cell types
- High mitochondrial density to provide ATP for ATPase pumps