Ion Channels

Question 1

For voltage-gated channels, what does it mean for it to be inactived?

Answer 1

Pore is blocked by the ball and chain mechanism, but the voltage gate is still on, the pore is not closed (fast)

Question 2

For voltage-gated channels, what does it mean for it to be deactived?

Answer 2

Voltage gate is off, the pore is closed (not blocked by the ball and chain)

Question 3

What is important for the P-domain (pore) to select the correct ions?

Answer 3

Charges on amino acid motif, width of channel