investigations Flashcards
Lyonization examples
Choroideremia
X-linked ocular albinism
X-linked RP
Lowe syndrome
Fabry diseases
What stage of embryology does X linked
Blastocyst
Appearance of lyonization on autofluorescence?
mottled appearance
Vfd defect seen with leber or ADoptic neuropathy ?
Cecocenteral - developement of pits
Lyonisation
X linked recessive dont noramlly appear in female.
If lyonisation occurs
X chromosome cancelled - severe effects
Increased autofluorescence on FAF
- OD
- Active melanoma
- Active optic neuritis
- Increased in RPE metabolism
- Best vitelliform
Decreased autofluorescence on FAF
- Birdshot chorioretinpathy
- Inactive melanoma
- Inactive optic neuritis
Blind spot location
temporal optic nerve head
15 degree temporal
5 vertical and 7 degrees horizontal
2/3 down on horizontal line
Centeral vfd
Unilateral
Optic nerve pathology: compressive lesions, optic neuritis
Macular pathology: scarring, oedema, etc
Bilateral
Optic nerve pathology: toxic/nutritional
Macular pathology: scarring, oedema etc.
Arcuate vfd
Glaucoma
Anterior ischemic optic neuropathy
Branch retinal artery/vein occlusion
Optic nerve drusen
PSD more sensitive than in MD in what condition ?
Glaucoma
Altiduinal defect
Horizontal meridian
1. Optic neuritis
Causes of binasal scotoma
Cause of binasal defect
Glaucoma in most cases
Compression of the temporal optic nerve/chiasm
Internal carotid artery aneursym
Infarction
PSD or MD better at monitoring glaucoma ?
MD
Where is drusen deposited in age-related macular degeneration
Drusen is situated between the basement membrane of the RPE and the Bruch’s membran