Investigation biochimique

Question 1

La majorité des analyses de biochimie sont effectuées sur des prélèvements
sanguins obtenus par ponction ________________.

Answer 1

veineuse

Question 2

What does the color of the cap indicate?

Answer 2

La couleur du bouchon indique quel est l’anticoagulant présent dans le tube.

Question 3

What do you get in Green Tube?

Answer 3

Heparine/ plasma heparine → anticoagulant → blood does not clot → you get all blood and plasma

Question 4

What do you get in Red Tube?

Answer 4

Tube Sec: Serum NO ANTICOAGULANT → Blood is clotted → you only get serum

Question 5

Difference between plasma vs serum:

Answer 5

Plasma has fibrogene, serum does not has fibrinogene

Question 6

What is a Biomarker:

Answer 6

composé biochimique dont la quantité chez un ensemble homogène de malades est statistiquement très éloignée de celle d’un ensemble de sujets sains, donnant un caractère discriminant à sa mesure

Question 7

Explain this? Sometimes a biomarker value will come as normal although the patient is sick:

Answer 7

This is because the levels in the blood of the marker will not increase immediatly. As such, if we believe that the marker should increase, we have to order another test for the next 3-4hours and see again. This is so that we can **trace the curve of increase in marker concentration over time. **

Question 8

What is Intervalle de reference?

Answer 8

valeurs dites “normales” ou “ de référence” réflètent la concentration de l’analyte biochimique en situation métabolique stable

différent pour le même marqueur selon le type de liquide biologique analysé
E.g. la concentration du sodium est différente dans le sérum et l’urine

Question 9

Often in medicine we are looking for an __________ marker for abnormal values

Answer 9

elevated