Introduction to pharmacogenomics

Question 1

What is pharmacogenomics?

Answer 1

The study of genomic influence on drug response

Question 2

What is pharmacogenetics?

Answer 2

Study of individual drug-gene interactions, usually one or two genes that have a dominant effect on a drug response

Question 3

What is G6PD deficiency?

Answer 3

Haemolytic reactions to primaquine, sulphonamides, aspirin, broad beans and infections
Results in haemolytic anaemia
Oxidative stress
X-linked characteristic
More common in certain races
Advantageous to malaria survival