Introduction to Neurones Flashcards

1
Q

What is the function of dendrites?

A

To receive inputs from other neurones and convey them to the cell body

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2
Q

What does the cell body do?

A

Integrate incoming signals that are conducted passively to the axon hillock

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3
Q

Why is an action potential most likely generated at the axon hillock?

A

As it contains the highest percentage of sodium channels

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4
Q

An axon mediates the transport of materials between what?

A

Soma and presynaptic terminal

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5
Q

What is a synapse?

A

The point of chemical communication between neurones

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6
Q

What are the types of neurones?

A

Unipolar
Pseudounipolar
Bipolar
Multipolar

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7
Q

Give an example of a unipolar neurone

A

Peripheral autonomic

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8
Q

Give an example of a pseudounipolar neurone

A

Dorsal root ganglion

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9
Q

Give an example of a multipolar neurone

A

Lower motor

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10
Q

What causes the upstroke of action potential in neurones?

A

Opening of voltage activated sodium channels

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11
Q

Once action potential is reached, what causes repolarisation?

A

Opening of potassium channels

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12
Q

What is the significance of a ‘leaky’ nerve cell membrane?

A

Passive signals do not spread far from site of origin

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13
Q

What ratio is used to calculate the distance which current spreads?

A

Membrane resistance/axoplasm resistance (referred to as lambda)

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14
Q

If lambda is increased will the action potential move along the axon faster or slower?

A

Faster

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15
Q

What substance is used to increase membrane resistance?

A

Myelin

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16
Q

What produces myelin in the CNS and PNS?

A

Schwann cells - PNS

Oligodendrocytes - CNS

17
Q

In myelinated axons, the action potential jumps between which structures?

A

Nodes of Ranvier

18
Q

What are the three main types of synapse?

A

Axodendritic
Axosomatic
Axoaxonic

19
Q

What are the two main functions of synapses?

A

To excite or inhibit

20
Q

What is the commonest excitatory synapse transmitter?

A

Glutamate

21
Q

What are the commonest inhibitory synapse transmitters?

A

GABA and glycine

22
Q

The excitatory potential is hyperpolarising/depolarising and the inhibitory potential is hyperpolarising/depolarising?

A

Excitatory - depolarising

Inhibitory - hyperpolarising

23
Q

Glutamate causes an increase in cation/anion conduction

A

Cation

24
Q

GABA and glycine activate neurotransmitters permeable to what?

A

Chloride