Introduction to immunobullous disorders

Question 1

What are immunobullous disorders?

Answer 1

These are skin conditions with blister formation as their primary feature

Question 2

What are some examples of immunobullous disorders?

Answer 2

• Pemphigus (vulgaris)
• Bullous pemphigoid
• Dermatitis herpetiformis

Question 3

How do blisters occur?

Answer 3

Blistering results from the breaking of cell connections within the skin, preventing it from staying together

This can be intra-epidermal or sub-epidermal

Question 4

What are some causes of blistering?

Answer 4

• Infection - Viral or bacterial
• Inflammatory conditions - Acute dermatitis
• Blistering drug eruptions
• Congenital conditions - Epidermolysis bullosa
• Autoimmune conditions - Immunobullous disorders
• Trauma - Burns, friction, insect bites
• Endocrine - PCT