INTRODUCTION TO HEMATOLOGY Flashcards

1
Q

Who describe worms in the blood?

A

Athanasius Kircher

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2
Q

Who discovered erythrocytes?

A

Swammerdam

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3
Q

In what year Athanasius Kircher described worms in the blood?

A

1657

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4
Q

In what year Swammerdam discovered erythrocyte?

A

1658

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5
Q

Who described human erythrocyte?

A

Anton Van Leuwenhoek

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6
Q

In what year Anton Van Leuwenhoek described human erythrocyte?

A

1674

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7
Q

In what year platelets were descibe?

A

1842

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8
Q

Who distinguished PMN from other leukocytes?

A

Wharton Jones

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9
Q

When did Wharton Jones distinguish PMN from other leukocytes?

A

1846

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10
Q

Who first complete classification of leukocytes?

A

Ehrlich

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11
Q

In what year Ehrlich complete classification of leukocytes?

A

1879

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12
Q

Who developed of wrights stain?

A

James Homer Wright

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13
Q

In what year James Homer Wright developed wrighg stain

A

1902

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14
Q

In what year hematology was considered a separate science from clinical pathology?

A

1920

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15
Q

-a

A

Without

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16
Q

-blast

A

Youngest / nucleated

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17
Q

-chomic

A

Color

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18
Q

-cyte

A

Cell

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19
Q

-Dys

A

Abnormal

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20
Q

-emia

A

In the blood

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21
Q

Ferro

A

Iron

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22
Q

Hyper-

A

Increased

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23
Q

Hypo-

A

Decreased

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24
Q

Iso-

A

Equal

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25
Q

Macro-

A

Large

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26
Q

Mega-

A

Very large / huge

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27
Q

Micro

A

Small

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28
Q

Myelo

A

Marrow

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29
Q

Normo

A

Normal

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30
Q

-Oid

A

Like

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31
Q

FBC

A

Full Blood Count

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32
Q

Fl

A

Femtoliter

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33
Q

Hb

A

Hemoglobin Concentration

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34
Q

Hct

A

Hematocrit

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35
Q

MCH

A

Mean Cell Hemoglobin

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36
Q

MCV

A

Mean Cell Volume

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37
Q

MCHC

A

Mean Cell Hemoglobin Concentration

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38
Q

CBC

A

Complete Blood Count

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39
Q

PG

A

Picogram

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40
Q

A life sustaining fluid which circulates through the heart and blood vessels

A

Blood

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41
Q

It carries oxygen and nutrients to the tissues and waste products to the lungs, liver and kidney where they can be removed from the body

A

Blood

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42
Q

What are the blood composition ?

A
  • formed elements
  • plasma
  • platelets
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43
Q

Includes erythrocyte, leukocytes, platelets, and plasma

A

Formed elements

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44
Q

Liquid portion of unclotted blood

A

Plasma

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45
Q

Fluid that remains after coagulation has occured and clot has formed

A

Serum

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46
Q

Composed of approximately 90% water and contains proteins, enzymes, hormones, lipids, and salts

A

Plasma

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47
Q

Normally appears hazy and pale yellow

A

Plasma

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48
Q

Normally appears clear and straw colored

A

Serum

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49
Q

What is the percentage of plasma?

A

55% of total blood

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50
Q

How long does blood coagulates in vitro?

A

5-10 mins

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51
Q

What is the total weight of the blood?

A

60-80ml/kg

52
Q

What is the total blood volume un adult male?

A

5-6 L

53
Q

What is the total blood volume in adult female?

A

4-5 L

54
Q

What is the TBV in newborn?

A

250-350 ml

55
Q

thickness and stickness of blood

A

Viscosity or blood viscosity

56
Q

What is the normal pH of blood?

A

7.35-7.45 (average of 7.40)

57
Q

pH of Venous blood

A

7.35

58
Q

pH of Arterial blood

A

7.45

59
Q

It is the ratio of the density of a substance to the density of a reference substance

A

Blood specific gravity

60
Q

Specific gravity is also called

A

Relative density

61
Q

What is the color of arterial blood

A

Bright red

62
Q

What is the color of venous blood?

A

Dark purplish red

63
Q

Concentration of solutes dissolved in the blood

A

Osmolality

64
Q

What is the instrument used to measure solutes?

A

Osmometer

65
Q

Enumerate the function of blood

A
  • respiratory
  • nutritional
  • excretory
  • buffering action
  • body defense mechanism
  • maintenance of constant body temperature
66
Q

Came from the greek work “haima”

A

Meaning blood

67
Q

A substance in which another is formed

A

Precursor

68
Q

Transport oxygen

A

RBC or erythrocyte

69
Q

Immune system

A

WBC or leukocytes

70
Q

Coagulation

A

Platelets or thrombocytes

71
Q

What are the waste products that can be remove via kidney

A

Creatinine and urea

72
Q

If there are more than 7.5 pH it is

A

Alkalosis

73
Q

If there are less than 7.3 pH it is

A

Acidosis

74
Q

Protein in plasma is around

A

7%

75
Q

Responsible for stopping the blood flow

A

Fibrinogen

76
Q

Maintain osmotic balance between blood and the tissue fluid

A

Albumin

77
Q

Proteins that are synthesized in the liver - for transport

A

Globulin

78
Q

How many grams of blood pero 100 mL

A

20 grams

79
Q

it is a measurement of the acidity of basicity of an aqueous solution

A

pH of blood

80
Q

Organs that are responsible in maintaining blood’s pH

A

KBL
K - kidney
B - brain
L - lungs

81
Q

Prevent the pH of blood to be acidic

A

Carbonate

82
Q

Work in internal fluid of the cells

A

Phosphate

83
Q

Binds to small amount of acid

A

Hemoglobin

84
Q

Specific gravity of whole blood

A

1.045-1.066

85
Q

Specific gravity of serum

A

1.024-1.028

86
Q

Specific gravity of plasma

A

1.025-1.029

87
Q

Reference range of osmolality

A

281-297 milliosmoles per kg or mOsms/kg

88
Q

What is the lifespan of platelets?

A

9-12 days

89
Q

What is the lifespan of erythrocyte?

A

120 days

90
Q

Phagocytic cells. Engulfs foreign substance. Has 2-5 lobes

A

Neutrophin

91
Q

Bluish black granules

A

Basophils

92
Q

Red orange granules

A

Eosinophils

93
Q

Largest WBC

A

Monocytes

94
Q

Transport oxygen from the lungs to the tissue and carbon dioxide from the tissue to the lungs

A

Respiratory

95
Q

Serves as a transport of blood and other materials to the different tissue of the body

A

Nutritional

96
Q

It pick up metabolic end product and delivers them to other organs for use

A

Excretion

97
Q

Helps maintain homeostasis

A

Buffering action

98
Q

Synthesized in the liver ; fight with infection

A

Globulin

99
Q

A cellular component of blood that lacks hemoglobin, has nucleus, and capable of motility

A

Leukocytes

100
Q

Size of thrombocytes

A

2-4 um

101
Q

Size of erythrocyte

A

7-8 um

102
Q

Pan

A

All/overall

103
Q

Phleb

A

Vein

104
Q

Phago

A

Eat/ingest

105
Q

Poikilo

A

Varied/irregular

106
Q

Poly

A

Many

107
Q

Schis

A

Split

108
Q

Scler

A

Hard

109
Q

Splen

A

Spleen

110
Q

Throm

A

Clot/thrombus

111
Q

Xanth

A

Yellow

112
Q

-osis

A

Increased

113
Q

-penia

A

Decreased

114
Q

Plasia

A

Formation

115
Q

Poiesis

A

Cell production

116
Q

Pro

A

Before

117
Q

Aniso

A

unequal

118
Q

SI units of hemoglobin

A

g/L

119
Q

SI units of cells

A

per uL or cells/L

120
Q

SI units of MCH

A

Pg or picogram

121
Q

SI units of MCV

A

Fl

122
Q

What is the major function of platelets

A

Coagulation for hemostasis

123
Q

Largest bone marrow

A

Megakaryotes

124
Q

What are the two important gases of respiratory?

A

Oxygen and carbon dioxide

125
Q

Enumerate function of the blood

A
  • respiratory
  • nutritional
  • excretory
  • buffering action
  • maintenance of constant body temperature
  • body defense mechanism
  • transportation of hormones and orher endocrine secretion that regulates cell function
126
Q

Reference range for osmolality?

A

281-297 milliosmoles per kilogram mOsms/kg