INTRODUCTION TO HEMATOLOGY Flashcards
1
Q
Who describe worms in the blood?
A
Athanasius Kircher
2
Q
Who discovered erythrocytes?
A
Swammerdam
3
Q
In what year Athanasius Kircher described worms in the blood?
A
1657
4
Q
In what year Swammerdam discovered erythrocyte?
A
1658
5
Q
Who described human erythrocyte?
A
Anton Van Leuwenhoek
6
Q
In what year Anton Van Leuwenhoek described human erythrocyte?
A
1674
7
Q
In what year platelets were descibe?
A
1842
8
Q
Who distinguished PMN from other leukocytes?
A
Wharton Jones
9
Q
When did Wharton Jones distinguish PMN from other leukocytes?
A
1846
10
Q
Who first complete classification of leukocytes?
A
Ehrlich
11
Q
In what year Ehrlich complete classification of leukocytes?
A
1879
12
Q
Who developed of wrights stain?
A
James Homer Wright
13
Q
In what year James Homer Wright developed wrighg stain
A
1902
14
Q
In what year hematology was considered a separate science from clinical pathology?
A
1920
15
Q
-a
A
Without
16
Q
-blast
A
Youngest / nucleated
17
Q
-chomic
A
Color
18
Q
-cyte
A
Cell
19
Q
-Dys
A
Abnormal
20
Q
-emia
A
In the blood
21
Q
Ferro
A
Iron
22
Q
Hyper-
A
Increased
23
Q
Hypo-
A
Decreased
24
Q
Iso-
A
Equal
25
Macro-
Large
26
Mega-
Very large / huge
27
Micro
Small
28
Myelo
Marrow
29
Normo
Normal
30
-Oid
Like
31
FBC
Full Blood Count
32
Fl
Femtoliter
33
Hb
Hemoglobin Concentration
34
Hct
Hematocrit
35
MCH
Mean Cell Hemoglobin
36
MCV
Mean Cell Volume
37
MCHC
Mean Cell Hemoglobin Concentration
38
CBC
Complete Blood Count
39
PG
Picogram
40
A life sustaining fluid which circulates through the heart and blood vessels
Blood
41
It carries oxygen and nutrients to the tissues and waste products to the lungs, liver and kidney where they can be removed from the body
Blood
42
What are the blood composition ?
- formed elements
- plasma
- platelets
43
Includes erythrocyte, leukocytes, platelets, and plasma
Formed elements
44
Liquid portion of unclotted blood
Plasma
45
Fluid that remains after coagulation has occured and clot has formed
Serum
46
Composed of approximately 90% water and contains proteins, enzymes, hormones, lipids, and salts
Plasma
47
Normally appears hazy and pale yellow
Plasma
48
Normally appears clear and straw colored
Serum
49
What is the percentage of plasma?
55% of total blood
50
How long does blood coagulates in vitro?
5-10 mins
51
What is the total weight of the blood?
60-80ml/kg
52
What is the total blood volume un adult male?
5-6 L
53
What is the total blood volume in adult female?
4-5 L
54
What is the TBV in newborn?
250-350 ml
55
thickness and stickness of blood
Viscosity or blood viscosity
56
What is the normal pH of blood?
7.35-7.45 (average of 7.40)
57
pH of Venous blood
7.35
58
pH of Arterial blood
7.45
59
It is the ratio of the density of a substance to the density of a reference substance
Blood specific gravity
60
Specific gravity is also called
Relative density
61
What is the color of arterial blood
Bright red
62
What is the color of venous blood?
Dark purplish red
63
Concentration of solutes dissolved in the blood
Osmolality
64
What is the instrument used to measure solutes?
Osmometer
65
Enumerate the function of blood
- respiratory
- nutritional
- excretory
- buffering action
- body defense mechanism
- maintenance of constant body temperature
66
Came from the greek work “haima”
Meaning blood
67
A substance in which another is formed
Precursor
68
Transport oxygen
RBC or erythrocyte
69
Immune system
WBC or leukocytes
70
Coagulation
Platelets or thrombocytes
71
What are the waste products that can be remove via kidney
Creatinine and urea
72
If there are more than 7.5 pH it is
Alkalosis
73
If there are less than 7.3 pH it is
Acidosis
74
Protein in plasma is around
7%
75
Responsible for stopping the blood flow
Fibrinogen
76
Maintain osmotic balance between blood and the tissue fluid
Albumin
77
Proteins that are synthesized in the liver - for transport
Globulin
78
How many grams of blood pero 100 mL
20 grams
79
it is a measurement of the acidity of basicity of an aqueous solution
pH of blood
80
Organs that are responsible in maintaining blood’s pH
KBL
K - kidney
B - brain
L - lungs
81
Prevent the pH of blood to be acidic
Carbonate
82
Work in internal fluid of the cells
Phosphate
83
Binds to small amount of acid
Hemoglobin
84
Specific gravity of whole blood
1.045-1.066
85
Specific gravity of serum
1.024-1.028
86
Specific gravity of plasma
1.025-1.029
87
Reference range of osmolality
281-297 milliosmoles per kg or mOsms/kg
88
What is the lifespan of platelets?
9-12 days
89
What is the lifespan of erythrocyte?
120 days
90
Phagocytic cells. Engulfs foreign substance. Has 2-5 lobes
Neutrophin
91
Bluish black granules
Basophils
92
Red orange granules
Eosinophils
93
Largest WBC
Monocytes
94
Transport oxygen from the lungs to the tissue and carbon dioxide from the tissue to the lungs
Respiratory
95
Serves as a transport of blood and other materials to the different tissue of the body
Nutritional
96
It pick up metabolic end product and delivers them to other organs for use
Excretion
97
Helps maintain homeostasis
Buffering action
98
Synthesized in the liver ; fight with infection
Globulin
99
A cellular component of blood that lacks hemoglobin, has nucleus, and capable of motility
Leukocytes
100
Size of thrombocytes
2-4 um
101
Size of erythrocyte
7-8 um
102
Pan
All/overall
103
Phleb
Vein
104
Phago
Eat/ingest
105
Poikilo
Varied/irregular
106
Poly
Many
107
Schis
Split
108
Scler
Hard
109
Splen
Spleen
110
Throm
Clot/thrombus
111
Xanth
Yellow
112
-osis
Increased
113
-penia
Decreased
114
Plasia
Formation
115
Poiesis
Cell production
116
Pro
Before
117
Aniso
unequal
118
SI units of hemoglobin
g/L
119
SI units of cells
per uL or cells/L
120
SI units of MCH
Pg or picogram
121
SI units of MCV
Fl
122
What is the major function of platelets
Coagulation for hemostasis
123
Largest bone marrow
Megakaryotes
124
What are the two important gases of respiratory?
Oxygen and carbon dioxide
125
Enumerate function of the blood
- respiratory
- nutritional
- excretory
- buffering action
- maintenance of constant body temperature
- body defense mechanism
- transportation of hormones and orher endocrine secretion that regulates cell function
126
Reference range for osmolality?
281-297 milliosmoles per kilogram mOsms/kg
