Introduction to cells Flashcards

1
Q

what is cytosol?

A

the water containing inorganic ions and small organic molecules

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2
Q

what is cytoplasm?

A

defines all contents and has a semi-solid consistency

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3
Q

structure of small cells?

A

simpler

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4
Q

advantages of smaller cells?

A

nutrients diffuse faster in smaller cells
adapt faster to enviornmental changes

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5
Q

what does the form of a cell tell you?

A

tells you about its function

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6
Q

how are red blood cells shape an indication of its function?

A

discoid shape
no nucleus provides large surface area for exchange of oxygen and carbon dioxide

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7
Q

how are epithelial cells shape an indication of its fucntipn?

A

microvilli providing cell polarity
increasing surface area for absorption

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8
Q

how are chondrocytes shapes an indication of their function?

A

‘embedded in thick extra cellular matrix proteins that hold water for cushioning’

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9
Q

what is the structure of nucleus?

A

membrane bound compartments
DNA packaged into chromosomes with nuclear matrix
nucleoli
surrounded by double membrane
nuclear pores
single, ovoid structure

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10
Q

what is the endoplasmic reticulum?

A

membrane folds

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11
Q

what happens to proteins in ER?

A

post translation modification

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12
Q

what does the ER store?

A

ca 2+ in muscle cells

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13
Q

what is the golgi apparatus?

A

stacks of flattened smooth membrane sacs and vesicles

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14
Q

function of golgi apparactus?

A

processing and sorting proteins
where proteins go through post translation modification

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15
Q

what is the function of mitochondrion?

A

source of ATP and energy source

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16
Q

structure of mitochondrion.

A

double membrane structure
contains its own circular DNA, RNA and ribosomes

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17
Q

exampels of small organelles?

A

lysosomes
endosomes
phagosomes
peroxisomes

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18
Q

what are lysosomes?

A

come from golgi apparatus and contain enzymes to break down proteins, carbs and lipids in acidic enviornments

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19
Q

what are endosomes for?

A

part of cytoplasmic membrane when lipoproteins and foreign bodies are brought inside cell

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20
Q

wat are phagosomes?

A

break down foreign bodies where the cytoplasmic membrane engulfs the cell and uses enzymes to kill the particle

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21
Q

what are peroxisomes?

A

involved in oxidation-reduction reaction

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22
Q

structure of cytoskeleton?

A

filamentous proteins forming internal scaffold
for cell shape and structure

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23
Q

what does cytoskeleton consist of?

A

microfilaments, intermediate filaments, microtubules

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24
Q

why do prokaryotes have less cytoskleleton?

A

cell wall provides strucutre

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25
what is the remaining weight of a cell made up of?
macromolecules
26
why is it important to know about cellular, molecular and structural biology?
treatments and disease act here modern drug development relies on this genetics is becoming more widespread
27
what is DNA packaged with?
with proteins into super coiled structure called chromatin
28
what does the DNA contain?
enzymes and proteins for regulation of DNA
29
what is nucleoli?
regions of RNA and protein
30
what are the nuclear pores in the nucleus for?
allow movement of small molecules
31
what other properties of nucleus are there?
some have multiple nuclei some have lobular nuclei
32
what are the different parts of golgi apparatus and what are their functions?
cis- receives protein lipids form ER trans- focuses on protein delivery stack-processes lipids and proteins
33
what else is the ER responsible for?
synthesis of lipids, steroids and detoxifies drugs in the liver
34
what are ribosomes?
site of protein synthesis
35
what are ribosomes made up of?
large and small subunits
36
what are microfilaments used for?
provides mechanical support and allows actin to bind to many different proteins
37
what are intermediate filaments used for?
mechanical strength for the resistance to stress
38
what are microtubules used for?
separation of chromosomes
39
properties of muscle cells?
specific protein fibres
40
what is the structure in skeletal cells?
contractile fibres arranged in sarcomeres
41
how does contraction happen in smooth muscle cells?
actin filaments arranged in cytoplasm with anchor points in cytoplasm and cytoplasmic membrane causing contraction by twisting
42
what is cytoplasmic membrane also known as?
plasma membrane, sarcolemma and plasmalemma
43
function of membrane?
controls what goes in/out of cell
44
what does contacts and interactions with neighbouring cells depend on?
properties of membrane molecules embedded in/on membrane
45
how does a ribosome get its structure?
rRNA fold and interact to give ribosome its 3D structure
46
what are bacteria?
prokaryotes
47
properties of bacteria?
DNA free in the cytoplasm circular form no nuclear membrane called nucleoid naked, extra chromosomal DNA smaller genome
48
differences between prokaryotes and eukaryotes?
smaller ribosomes in prokaryotes faster replication of DNA in prokaryotes prokaryotes don't have membrane-bound intracellular organelles most prokaryotes have a cell wall that include distinctive molecules
49
what is the importance of cell wal?
structure, shape and preventing osmolysis
50
what is the daigram of simplified bacteria structure?
slide25 Microsoft PowerPoint - Introduction to cells_LDKB_2024
51
what are viruses?
'small entities that require a host to live in' evolve fast 'Supramolecular structures of nucleic acids, proteins and sometimes lipids and carbohydrates' 'need to infect a cell and use its machinery to reproduce' 'Simple genomes, but genetic organization varies among viruses'
52
what are the structural organizations of viruses?
naked enveloped
53
what is a simple diagram of virus?
slide 28 Microsoft PowerPoint - Introduction to cells_LDKB_2024
54
what is the purpose of a capsid?
protect viral genome
55
what are capsomers?
viral proteins that assemble protecting genetic material because produce have specific shapes
56
what is tissue tropism?
capsomeres bind to receptors on cell surface and the virus invades the cell
57
how do some viruses make host cell recognition easier?
they have membrane envelope that surrounds the capsid
58
what are the properties of naked viruses?
'they contain capsid only Includes; Papilloma virus, Polio, Hepatitis A'
59
what are the properties of enveloped viruses?
the capsid is surrounded by lipid layer or envelope obtained from host cell membrane
60
what does the envelope contain?
'viral proteins for infecting specific cell types'
61
examples of enveloped viruses?
HIV, Influenza A and B, Coronaviruses