Introduction to Arthritis Exam 1 Flashcards

1
Q

Components of a patient evaluation for joint pain

A
  • History
  • Physical examination
  • Laboratory tests
  • Imaging
  • Synovial fluid analysis
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2
Q

What are elements in patient history?

A
  • Pain
  • Stiffness
  • Deformity
  • Loss of function
  • Systemic illness
  • Extra-articular involvement
  • Other medical conditions that predispose to or affect expression of arthritis
  • Family history of arthritis or associated conditions
  • Activities that predispose to arthritis
  • Joint injury
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3
Q

What are elements in physical examination?

A
  • Synovial inflammation
  • Instability
  • Deformity
  • Crepitus
  • Distribution will help tell us which type of arthritis is involved
  • Skin
  • Eyes
  • Oropharynx
  • Lungs, heart, abdomen, nervous system
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4
Q

What is there to look for in synovial inflammation?

A
  • Redness (rubor)
  • Swelling (effusion or soft tissue swelling)
  • Heat (calor)
  • Pain (tenderness)
  • Loss of function (movement)
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5
Q

What is crepitus?

A

sounds or crackling that can be heard as the joint is being felt or being put through its range of motion

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6
Q

How can instability and deformity happen?

A

when join exposed to inflammation over a long period of time

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7
Q

What are you looking for when evaluating the skin?

A
  • rash
  • nodules
  • texture
  • tophi (urate deposits)
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8
Q

What are you looking for when evaluating the eyes?

A
  • dryness
  • corneal disease
  • episcleritis / scleritis
  • uveitis
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9
Q

What are the lab tests conducted when differentiating between the forms of arthritis?

A
  • CBC
  • Chemistry
  • Uric acid, creatine kinase (CK)
  • Urinalysis
  • Inflammatory markers
  • Autoantibodies
  • Complement
  • Synovial fluid analysis
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10
Q

What is included in the chemistry lab test?

A
  • albumin
  • creatinine
  • liver function tests
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11
Q

What are the inflammatory markers?

A
  • erythrocyte sedimentation rate (ESR)

- C-reactive protein (CRP)

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12
Q

What are the autoantibodies?

A
  • ANA (Anti-nuclear antibodies) and other lupus-related autoantibodies
  • RF (rheumatoid factor) and anti-CCP (cyclic citrullinated peptide) antibodies
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13
Q

What is included in the synovial fluid analysis?

A
  • appearance
  • cell count
  • gram stain
  • crystal analysis
  • special studies
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14
Q

What are the imaging studies conducted when differentiating between the forms of arthritis?

A
  • Xray
  • CT scan
  • MRI
  • Ultrasound
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15
Q

Xray

A
  • In inflammatory arthritis, can see: Soft tissue swelling, Peri-articular demineralization, Articular erosions, Characteristic distribution
  • In degenerative arthritis, can see: Reactive bone formation (osteophytes on edges of the joints), Joint space narrowing (loss of cartilage), Joint deformity
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16
Q

What are the different classes of arthritis?

A
  • Osteoarthritis and other degenerative diseases
  • Rheumatoid arthritis, lupus, and other autoimmune rheumatic diseases
  • Spondyloarthritis (spondyloarthropathy): Ankylosing spondylitis, Psoriatic arthritis, Reactive arthritis, Arthritis of inflammatory bowel disease, Undifferentiated spondyloarthropathy
  • Crystal arthritis: Gout, Pseudogout
  • Infectious arthritis: Bacterial, Post-viral, Fungal