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OU Module GI/Rheum > IBD Drugs > Flashcards

IBD Drugs Flashcards

1
Q

Sulfasalazine ADE

A

GI upset, rash, headache, arthralgias, hypersensitivity, aplastic anemia, fever, hepatotoxicity

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2
Q

Sulfasalazine Counseling

A

Take with food.
Improvement takes 4+ weeks; extended release agents
should not be crushed or chewed. Impairs folic acid absorption

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3
Q

Mesalamine ADE

A

Headache, abdominal pain, nausea, eructation, edema, dizziness, fever, pharyngitis

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4
Q

Mesalamine Counseling

A

Extended release agents should not be crushed or chewed; avoid antacids, H2RAs, PPIs

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5
Q

Olsalazine ADE

A

dose-related secretory diarrhea

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6
Q

Balsalazide ADE

A

headache, abdominal pain

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7
Q

Corticosteroids ADE

A

HPA axis suppression, increased risk of infection, immunosuppression, ↑glucose, ↑WBC, ↑ BP, weight gain, edema, alteration in mood/insomnia, osteoporosis (long term)

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8
Q

Corticosteroids Counseling

A

take oral preps with food to decrease stomach upset, do not stop abruptly

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9
Q

Azathioprine ADE

A

hepatosplenic T-cell lymphoma, n/v/d, infection, neutropenia, hair loss, pancreatitis, hepatotoxicity, nephrotoxicity, myelosuppression

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10
Q

Mercaptopurine ADE

A

hepatosplenic T-cell lymphoma, infection, neutropenia, nausea, hair loss, pancreatitis, hepatotoxicity, myelosuppression

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11
Q

Cyclosporine ADE

A

hypertrichosis, n/v, hyperglycemia, nephrotoxicity, HTN, hepatotoxicity, neurological toxicity, headache, infection, hyperuricemia

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12
Q

Methotrexate ADE

A

myelosuppression, hepatotoxicity, pulmonary toxicity

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13
Q

Metronidazole ADE

A

metallic taste, disulfiram-like reaction, nausea, paresthesias, glossitis, peripheral neuropathy with long-term use

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14
Q

Metronidazole Counseling

A

disulfiram-like reaction with alcohol

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15
Q

Ciprofloxacin Counseling

A

avoid taking with Ca2+ or iron products, vitamins, dairy

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16
Q

Infliximab ADE

A

infection, infusion reaction, fever, myalgias, hepatosplenic T-cell lymphoma, headache, nausea, diarrhea

17
Q

Adalimumab ADE

A

infections, injection site reaction, headache, rash, hepatosplenic T-cell lymphoma, elevated CK

18
Q

Certolizumab pegol ADE

A

infections, arthralgias, hepatosplenic T-cell lymphoma, headache

19
Q

Tysabri: Leukocyte Adhesion and Migration Inhibitors ADE

A

PML (progressive multifocal leukoencephalopathy), URI, headache, nausea, fatigue

OU Module GI/Rheum (30 decks)

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