Introduction sepsis and septic shock

Question 1

What was sepsis previously called?

Answer 1

Systemic inflammatory response syndrome (SIRS)

Question 2

What was septic shock previously called?

Answer 2

Severe sepsis

Question 3

What is sepsis?

Answer 3

-life threatening organ dysfunction caused by dysregulated host response to an infection

Question 4

How does sepsis manifest?

Answer 4

1. systemic inflammation
2. coagulation
3. tissue hypoperfusion lead organ failure

Question 5

What is shock?

Answer 5

• circulatory collapse
• arterial BP too low to maintain adequate supply blood to tissues
• subset of patients with increases in mortality
• result underlying:
  1. circulatory
  2. cellular
  3. metabolic abnormalities

Question 6

Symptoms of shock

Answer 6

1. cold
2. pale
3. sweaty skin
4. weak
5. rapid pulse
6. irregular breathing
7. decreased consciousness
8. reduced flow urine

Question 7

What are 4 types of shock ?

Answer 7

1. Hypovolaemic
2. Cardogenic
3. Septic
4. Neurogenic
   SNCH

Question 8

What is SOFA?

Answer 8

sequential organ failure assessment

- identify ICU patients suspect of having sepesis

Question 9

What is qSOFA?

Answer 9

quick sequential organ failure assessment

• • > than 2 criteria
• used under-resourced settings where no lab
  1. resp rate > 22 bpm
  2. altered mental act
  3. systolic BP <100mmHg