Inotropic therapy Flashcards
1
Q
When is inotropic therapy initiated?
A
- fluid resuscitation is ineffective
2
Q
How effective is inotropic agents in treating sepsis?
A
treat life threatening hypotension + improve cardiac output
3
Q
why are adrenergic agents titrated slowly ?
A
due to complications like tachycardia + myocardial ischaemia
4
Q
MOA and use adrenaline (epinephrine)
A
- 1st line
- non-selective alpha , B adrenergic agonist
- increase CO + peripheral vasoconstriction
- increase lactate level = impair BF to splanchnic system (internal organs )
5
Q
MOA Dobutamine
A
- B-adrenergic agonist = increase CO + O2 delivery
- ONLY used in septic patients - adequate filling pressure + BP + low CO
6
Q
Dose of dobutamine
A
2-20mcg/kg/min - adults
5-15 mcg/kg/min - children
= increase CO , but HR increases significantly
7
Q
MOA Dopamine
A
- alpha, B adrenergic agonist with dopaminergic activity
8
Q
Low dose of dopamine 1-5mcg/kg/min
A
- maintain renal perfusion
= not used for renal protection as part of sepsis
9
Q
High dose dopamine > 5mcg/kg/min
A
- exhibit alpha + B-adrenergic act
- support BP
- improve cardiac func
= increase SV + HR
10
Q
causes of dopamine
A
- tachycardia
- potential arrhythmia
- not used routinely for management septic shock