Introduction

Question 1

earliest response to infection

Answer 1

innate immunity

Question 2

not “antigen specific”

Answer 2

innate immunity

Question 3

no memory

Answer 3

innate immunity

Question 4

• Skin/mucosa

- movement of mucus by cilia

Answer 4

mechanical barriers

Question 5

hormones of the immune system

Answer 5

cytokines

Question 6

released by liver during acute inflammation

Answer 6

C-reactive protein (CPR)

Question 7

phagocytic celles, that are antigen presentation to T cells

Answer 7

macrophages

Question 8

major white blood cell, polymorphonuclear

Answer 8

neutrophil

Question 9

killing parasites/ allergies

Answer 9

eosinophils

Question 10

allergic releases histamine and response to parasites especially helminths

Answer 10

Mast cells

Question 11

can kill some virus-infected cells and some tumor cells

Answer 11

Natural killer cell

Question 12

found in tissues and function to detect infection and elicit an innate response

Answer 12

dendritic

Question 13

sentry/guard cell that detect infection and activates adaptive immune response

Answer 13

Dendritic cells

Question 14

cells of the innate immune have receptors for pathogens

Answer 14

pattern recognition receptors

Question 15

microbial product recognized by a PRR

Answer 15

pathogen associated molecular pattern

Question 16

LPS infection?

Answer 16

gram negative bacteria

Question 17

example of a PRR that recognizes LPS

Answer 17

TLR-4

Question 18

innate cell gets triggered and leads to the production of inflammatory cytokines

Answer 18

IL-1, IL-6 and TNF

Question 19

fever caused by cytokines?

Answer 19

IL-1

Question 20

host defenses mediated by the clonal expansion and differentiation of antigen-specific lymphocytes

Answer 20

adaptive immunity

Question 21

requires sensitization by antigen

Answer 21

adaptive immunity

Question 22

develops over days/weeks

Answer 22

adaptive immunity

Question 23

mediated by antigen-specific antibosies and produced by activated B cells

Answer 23

humoral immunity

Question 24

antibodies can be transferred to non-immune recipients by immune serum

Answer 24

antiserum

Question 25

adaptive immune response primarily involving antigen-specific T-lymphocytes

Answer 25

cell-mediated

Question 26

first immune response to antibody

Answer 26

primary antibody response

Question 27

increase in response to antibody due to memory

Answer 27

secondary antibody response

Question 28

results in the expansion of antigen specific B and T cells clones

Answer 28

clonal selection

Question 29

each specific lymphocyte is

Answer 29

specific for one antigen

Question 30

if the antigen is exposed to B cell it will go through clonal selection leading to proliferation and producing

Answer 30

Clone of memory B cells and clone of plasma cells that secrete antibodies

Question 31

antibody response are

Answer 31

polyclonal

Question 32

the shape that the antibody recognizes and bind we call the

Answer 32

epitope

Question 33

• bone marrow

- thymus

Answer 33

primary lymphoid organs

Question 34

• adenoid
• tonsil
• lymph nodes
• spleen
• peyer’s patches

Answer 34

secondary lymphoid organs

Question 35

we have antigen-specific receptors for everything even if we have not been exposed of it?

Answer 35

YES!!

Question 36

H-chains

Answer 36

heavy chains

Question 37

L-chains

Answer 37

light chains

Question 38

For a particular antibody, the H-chains are _______ and the L-chains are _______

Answer 38

identical for both!

Question 39

N-terminal is

Answer 39

variable

Question 40

C-terminal is

Answer 40

constant