Antibody function Flashcards

exam 3

1
Q

myeloma cells produce large amounts of one particular

A

monoclonal

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2
Q

antibody is the same as

A

immunoglobin

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3
Q

myeloma is when a ______ becomes myeplastic

A

plasma cell

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4
Q

myeloma cells tend to home to the

A

bone marrow

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5
Q

hypervariable region contains

A

CDR= complementarity determining region

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6
Q

Immunoglobulin classes isotypes is changess in the

A

heavy chains

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7
Q

light chains will have wither a

A

kappa or lamba chains

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8
Q

plasma cell secretes _____ IgM

A

pentameric

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9
Q

plasma cell secretes _____ IgA

A

dimeric or monomeric

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10
Q

every B cell receptor has a signaling complex/ heterodimer called

A

Ig-alpha/Ig-beta

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11
Q

clumping antigen

A

Agglutination

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12
Q

blocking fusion event

A

viral neutralization

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13
Q

IgG functions as an important

A

opsonin

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14
Q

The phagocytes’s _____ receptros mediate opsonization

A

Fc-gamma

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15
Q

Aggregation of immunoglobin on bacterial surface allows _________ of Fc receptors

A

cross-linking

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16
Q

cells express an Fc-gammaR

A

Nature killer cells

17
Q

induce some virus-infected or tumor cells to undergo apoptosis

A

NK cells

18
Q

activation via IgW crosslinking ( Fc-epsilonR)

A

Mast cell

19
Q

immunity to worms

A

Mast cells

20
Q

found near mucosal surfaces s

A

IgE

21
Q

baby inside the womb has

A

maternal IgG

22
Q

baby will receive _____ in milk

A

dimeric IgA

23
Q

Secretory component protein found in the Ig in secretions and mucosal sites

A

IgA

24
Q

antigen-binding fragments

A

scFv

25
Q

can be coupled to various molecules or cells to link antigen specificity and effector function

A

scFv