Intro To Reproduction Flashcards

1
Q

Basics of reproduction
-essential/non essential for what
-the only system that differed between males and females

A

Essential for survival of species but not specifically animal

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2
Q

Female generates mature egg called…
-function in reproduction

A

Oocyte
-Receives germ cells from male
-Facilitates fertilisation, implantation
-Nurtures embryonic and fetal growth
-Deliver foetus
-Provide nourishment in early life

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3
Q

Male role of reproduction

A

Production of mature sperm for fertilisation

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4
Q

Name the parts of female sex organ

A

On anki cards repro

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5
Q

What organ controls the gonads of reproductive system

A

Brain (hypothalamus)—>controls activity of pituitary gland that release the hormones which activate gonads

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6
Q

What is the gonad

A

The part of the reproductive system that produces and releases eggs (ovary) or sperm (testicle/testis)

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7
Q

Which hormone links the hypothalamus to the pituitary gland (regulates reproduction)

A

Gonadotrophin Releasing Hormone (GnRH)

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8
Q

What type of hormone is GnRH (Gonadotrophin Releasing Hormone)?

A

decapeptide protein hormone

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9
Q

Size of decapeptide protein hormone and cleaved between what positions of amino acids?

A

Very small molecule
Between positions 6 & 7

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10
Q

Communication between the pituitary gland and the gonads is via which hormones

A

Luteinising Hormone
(LH) and
Follicle Stimulating Hormone (FSH)

(Both are a type of gonadotropin hormone)

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11
Q

The LH and FSH are released from what lobe of pituitary gland?

A

Anterior pituitary

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12
Q

LH and FSH are both types of

A

Gonadotrophin hormones

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13
Q

Where is Hypothalamic pituitary system/ reproductive axis found?

A

Sits at base of brain

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14
Q

Name the structures of the hypothalamic-pituitary system and more structures

A

On anki cards repro

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15
Q

Posterior pituitary gland forms from….

A

Hypothalamus during foetal life
I.e anterior and posterior come from different structures

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16
Q

Which fluid is found in the hypothalamus?

A

Third ventricle cerebrospinal fluid (CSF)

17
Q

What is the median eminence?
-where is it found

A

Structure at the base of hypothalamus
-critical area where hormones coming from hypothalamus are released to go into pituitary gland

(Neuro hemo organ containing capillary Bed into which hypothalamic neurosecretory fibres will release their hormones)

18
Q

Once hormones released into median eminence how are they transmitted to anterior pituitary?

A

Transmitted through blood vessels called hypophysial portal system (portal vessel)

19
Q

Location of the GnRH neurone cell bodies?
Where do they project their neurones to?

A

Found in preoptic area
Terminals of GnRH nerurones lie down at region called arcuate nucleus (the arch)

20
Q

Why are the GnRH hormones released first into portal vessels after being in median eminence and not transported straight to bloodstream?

A

Have very short half life so have to released somewhere near to quickly get degraded and activated

21
Q

The GnRH release pattern is…

A

Pulsatile (beating rythmically)

22
Q

Where are gonadroph cells found?
What do they contain?

A

-Anterior pituitary gland
-Contain GnRH receptors for the GnRH hormone

23
Q

GnRH must be released in a …

A

Pulsatile manner for it to have an intracellular effect

24
Q

What are the similarities & differences between structures of LH and FSH hormones

A

-both have same alpha subunit but different beta subunits
-both containing N-linked glycosylation sites

25
LH is released every single time ____________ is released FSH on the other hand…
GnRH is released Does not follow pattern of GnRH release (only during surge which happens just before ovulation) (anki cards diagram)
26
Name the functions of the ovaries
On GoodNotes
27
Reproduction in female. Is regulated by which axis? Reproduction in male. Is regulated by which axis?
hypothalamo-pituitary- ovarian axis hypothalamo-pituitary- testicular axis
28
Name the functions of the testes
On goodnotes
29
Gonadotrophins stimulate secretion of which steroid and peptide hormones from ovaries?
Oestradiol Progesterone Androgens
30
Most hormone release from ovaries is positive or negative feedback?
Negative
31
Which hormone release is the only exception to not being a negative feedback but positive?
Oestradiol in females during surge & lead up to ovulation of egg
32
Is the pattern of GnRH release important?
YES
33
What makes up the HPG (hypothalamic–pituitary–gonadal axis)
Hypothalamus, pituitary gland and testis/ovary