Intro to Psychopharmacology Flashcards
What is pharmacology?
Scientific study of the actions of drugs and their effects on living things.
what is neuropharmacology?
Drug-induced changes in the functioning of cells in the nervous system.
What is psychopharmacology?
Study of drug-induced changes in mood, thinking and behaviour.
what are the two main types of reasons why people take psychoactive drugs?
Recreational and therapeutic.
Give some examples of recreational reasons for people taking psychoactive drugs.
Increased energy
Euphoria
Relaxation
Hallucinogenic
Empathogenic
Give some examples of therapeutic
reasons for people taking psychoactive drugs.
Anxiety
depression
Schizophrenia
Insomnia
ADHD
What are the three drug classifications?
Depressants
Stimulants
Hallucinogens
Give examples of drugs that are depressants.
Alcohol
Benzodiazepines
Opioids
Cannabis
Give examples of drugs that are stimulants.
Caffeine
Cocaine
Methamphetamine
Nicotine
Give examples of drugs that are hallucinogens.
LSD
Ketamine
Cannabis (at high concentrations)
MDMA (at high concentrations)
In general, how do drugs influence behaviour?
Have effects on neurotransmitters in the central nervous system.
How many neurotransmitter chemicals have been identified?
> 100
Give 4 examples of neurotransmitter classes.
Amino acids, monoamines, acetylcholine, neuropeptides.
What is classification of neurotransmitte4rs based on?
Chemical and molecular properties
Give two examples of amino acid neurotransmitters.
Gamma-aminobutryic acid (GABA)
Glutamate
What is GABA?
Most common inhibitory neurotransmitter in the CNS.
In general, how does GABA work?
During stressful situations, neurons can be hyperactive. GABA reduces stimulation.
Knowing how GABA works, what is an example of a medication type that may target GABA?
Seizure medication
What is glutamate?
Most common excitatory neurotransmitter in CNS
What are the two major categories of transmitter receptors?
Ionotropic and metabotropic
True or false: all neurotransmitters are affected by psychoactive drugs that lead to a change in behaviour
False. Most are not significantly affected.
How can drugs alter synaptic transmission and nt availability?
Through indirect or direct interactions
In what type of cases can psychopharmacology be relevant?
Homicide trials
Sexual assault cases
Impaired driving cases
How might forensic psychopharmacology be used in a homicide trial?
Explain actions/behaviours of accused and deceased.
What types of information is a toxicologist able to provide in assisting forensic cases?
What is the drug
Time duration of the effects
Concentration
Typical side effects
What types of information is a psychologist/psychiatrist able to provide in assisting forensic cases?
Underlying mental health disorders
Was the individual able to consent/know what they were doing.
Perceptions of situations e.g., threats
What is the most frequently detected drug in forensic cases?
Alcohol
How does alcohol affect behaviour?
Aggression
Memory
What is automatism?
An individual is unaware of their behaviour and has no conscious control over it.
What is a common effect of automatism?
Partial or full amnesia afterwards
What is a blackout?
Memory loss.
Failure to recall events during the period of intoxication.
Why does alcohol not cause automatism?
As BAC increases, brain activity is reduced. So once consciousness is reduced, phsyical activity is no longer possible.
What types of drugs induce automatism? Give examples
Dissociative anesthetics
e.g., ketamine, PCP, Z drugs
Is cocaine-induced psychosis automatism?
No. Consciousness is still present, thus not fitting criteria.
What is ambien?
Short acting sedative prescribed for insomnia
What is important to keep in mind when it is stated certain side effects “have been reported”?
Means these were instances documented outside of controlled clinical trials, meaning it would have no other data on whether additional influences played a role.
What is sleep-driving?
Driving while not fully awake with amnesia for the event
What are important questions in trial when a prescription medication is under scrutiny?
Was the medication being taken as prescribed? Was it taken with other substances?