Benzodiazepines Flashcards
1
Q
What was the first BDZ to be introduced?
A
Chlordiazepoxide
2
Q
Describe the benefits of chlordiazepoxide.
A
First true anxiolytic without excessive sedation
Low incidence of tolerance
Wide therapeutic index
3
Q
Describe the core chemical structure of BDZs.
A
A benzene ring and a diazepine ring
4
Q
Give 8 clinical features of BDZs as discussed in class.
A
Agitation
Aggression
Violence
Impulsivity
Irritability
Confusion
5
Q
What do BDZ effects on CNS depend on?
A
Dose
6
Q
What are paradoxical reactions?
A
Reactions to the drug that are the opposite of what is expected.
7
Q
What is suggested to be the most important factor for paradoxical reactions in BDZs?
A
Underlying personality
8
Q
A
