Intro to Medical Microbiology Flashcards

1
Q

the three domains of life

A
  • Bacteria (Prokaryote)
  • Archaea (Prokaryote)
  • Eucarya (Eukaryotes)
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2
Q

Procaryotes are

A

single-cell organisms that do not have a nucleus and lack membrane-bound organelles.

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3
Q

microbiology is the study of

A

micro organisms

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4
Q

applied microbiology is

A

medical microbiology

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5
Q

basic microbiology is

A

cellular microbiology.

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6
Q

Microbial causes of infection

A
  • Bacteria – Prokaryotic
  • Viruses – unclassified
  • Fungi – Eukaryotic
  • Parasites – Eukaryotic (usually [can be vector for
    prokaryotes])
  • Prions – unclassified
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7
Q

Bacterium:

A

Chiefly round, spiral or rod shaped single celled prokaryotic organism that typically lives in soil, water, organic matter or the bodies of plants and animals

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8
Q

Virus:

A

A unique, acellular, metabolically inert organism that only replicates within living cells.

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9
Q

Fungus:

A

Any of a kingdom of saprophytic (an organism which gets its energy from dead and decaying organic matter) and parasitic spore-producing eukaryotic typically filamentous organisms including moulds, yeasts, mushrooms and yeasts

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10
Q

Parasite:

A

An organism living in, with or on another organism

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11
Q

Prion:

A

Protein of unknown function that resides on the surface of brain cells. An abnormal form of prion protein that in mammals includes pathogenic forms that:

  • arise spontaneously (e.g. genetic mutation)
  • transmission (e.g. via infected tissue)

Upon accumulation in the brain cause a prion disease
e.g. BSE or CJD.

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12
Q

In micro-organisms size matters as

A

they can help determine what type of organism they are as they are sized differently.

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13
Q

Parasites size

A

microscopic to over 30m

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14
Q

Fungi size

A

2 to 10μm

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15
Q

Bacteria size

A

0.2 to 0.5μm

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16
Q

Viruses

A

20 to 400nm

17
Q

Prions

A

10nm (often measured in Angstrom [1A=0.1nm])

18
Q

Multi-disciplinary team (MDT) consists of:

A
  • Medical Microbiologists and Virologists
  • Laboratory Manager.
  • Clinical scientists.
  • Biomedical Scientists.
  • Healthcare support workers.
  • IT.
19
Q

What does a medical microbiologist do?

A
  • Advise on the diagnosis of infection.
  • Review laboratory results.
  • Advise on interpretation of results.
  • Advise on management of infection(antimicrobials).
  • Telemedicine or ward review.
  • Infection prevention and control.
  • Develop policies and guidelines.
  • Work as part of a MDT
20
Q

sterile parts of the body

A
  • blood.
  • cerebrospinal fluid (CSF)
  • bone. includes: bone marrow
  • joint fluid. includes: synovial fluid
  • pleural fluid. includes: chest fluid
  • peritoneal fluid. includes: abdominal fluid
  • pericardial fluid.
21
Q

non-sterile parts of the body

A
  • Brain
  • oesophagus
  • lungs
  • large intestine
22
Q

Sputum used for

A

lower respiratory tract infection.

23
Q

Throat swab used for

A

tonsillitis

24
Q

swab used for

A

wound infection ,genital tract infection.

25
Q

Faeces used for

A

infectious diarrhoea

26
Q

Blood culture used for

A

septicaemia (sepsis).

27
Q

Cerebrospinal fluid (CSF) used for

A

meningitis.

28
Q

Aspirate of pus used for

A

abscess

29
Q

Bone used for

A

osteomyelitis

30
Q

Gram stain used

A

to visualise bacteria and yeasts/fungi

31
Q

Special stains

A

Ziehl Neelsen stain or auramine stain for Mycobacteria.

32
Q

viruses not visible in

A

light microscope