Intro to Immunology - Hunter Flashcards
What is the number one public health concern on the planet?
Malnutrition
(blank) has prevented more illness and mortality than all other interventions combined.
Vaccination
How are infectious agents removed using innate immunity within 0-4 hours?
Agents recogniezed by non-specific and broadly specific effectors
Early induced innate response from 4-96 hours removes infectious agents how?
- Recognition of microbial-assocated molecular patterns
- Inflammation and recruitment of effector cells
- Removal of agent
Nearly all cells of the immune system stem from what system/structure?
Bone marrow
What more complicated type of immune response happens after innate immunity?
Adaptive
What type of immunity transports the antigen to lymphoid organs?
Adpative
Recognition by B and T cells happens in what type of immunity>
Adaptive
Describe the adaptive immune response?
- transport antigen to lymphoid organs
- recognition by B and T cells
- clonal expansion and differentiation of B/T into effectors
- removal of agent
(myeloid, lymphoid, erythroid) cell line is active in innate immunity
myeloid
which cell type handles viral infections in innate immunity?
NK cells
what are dr. hunter’s favorite cells?
MACROPHAGES
What is the function of neutrophils?
phagocytosis and killing of microorganisms
What is the function of eosinophils?
killing of antibody-coated parasites through release of granule contents
what is the function of basophils?
controlling immune response to parasites
what is the function of macrophages?
phagocytosis and killing of microorganisms; activation of T-cells and initiation of immune responses
what is the function of megakaryocytes?
platelet formation and wound repair
what is the function of erythrocytes>
oxygen transport
what is the function of dendritic cells?
activation of T-cells and initiation of ADAPTIVE immune response
what is the function of mast cells?
expulsion of parasites form body through release of granules containing histamine and other active agents
what is the function of monocytes?
circulating precursor to MACROPHAGES
What are the three differentiated types of lymphoid cells found in the tissues?
Plasma cells, effector T cells, and NK cells
What are the two types of lymphoid cells found in the blood?
B cells and T cells
What three types of myeloid cells are found in the tissues?
Dendritic cells, macrophages, and mast cells