Intro to Immunology Flashcards
What are the living agents that can replicate in a host? (4)
Viruses, Bacteria, Fungi, and Parasites (protozoa and Helminths)
T/F: The innate immune system is specific.
False
T/F: The adaptive immune system is specific.
True
What defensive antimicrobial enzyme is known to digest bacterial cell walls?
Lysozyme/defensins
What is the function of mucous?
Prevent attachment of organisms.
Which part of the Innate Immune system is known as “professional killers?”
Neutrophils
Which cells are know to capture antigens in one location and present in another?
Dendritic cells
T/F: Inflammation is an adaptive immune system cell response.
False; Inflammation is an innate immune cell response.
T/F: antibodies kill pathogens.
False, Antibodies mark (opsonize) a target for destruction.
What are B cell receptors?
Antibodies
What is the basis for immunization?
memory
What are the three types of T cells?
helper, killer and regulatory T cells
What stimulates proliferation of Tcells and B cells?
cognant antigen
What is required by T cells for activation?
Antigen presentation
What are the three main antigen presenting cells?
dendritic cells, macrophages, and B cells
What does MHC stand for?
Major histocompatibility complex
What hormone-like messengers are produced especially by T helper cells and communicate with both immune and non immune cells?
Cytokines
interleukins (IL-1, IL-2, etc), interferon y, and TNF (tumor necrosis factor) are examples of what?
Cytokines
What type of proteins function as billboards to display chopped up peptides?
MHC (major histocompatibilty complex) proteins
Which type of MHC proteins are found on virtually all cells of the body?
Class I
Which type of MHC proteins display what cells are producing inside for killer T cells to scan?
Class I
Which type of MHC proteins are found typically on APC?
Class II
Which type of MHC proteins display what has been killed at the battle site in order to inform T helper cells about the battle?
Class II
Which immune system is faster, determines which weapons to be used and has a hard wired memory?
Innate
What are the four types of Granulocytes?
Neutrophils, Basophils, Mast cells, and eosinophils
Which granulocyte is by far the most common of circulating white blood cells?
Neutrophils
What are the different types of Monocytes?
Macrophages and Dendritic cells
Which type of monocyte can also arise from lymphoid lineage as well as myeloid lineage?
Dendritic cells
Which is the more abundant WBC: Granulocytes or monocytes?
Granulocytes
what are the three types of WBCs of lymphoid lineage?
B cells, T cells, and NK cells
Which type of lymphoid WBCs are adaptive?
B cells and T cells; NK cells are innate
