Intro to Immunology

Question 1

What are the living agents that can replicate in a host? (4)

Answer 1

Viruses, Bacteria, Fungi, and Parasites (protozoa and Helminths)

Question 2

T/F: The innate immune system is specific.

Answer 2

False

Question 3

T/F: The adaptive immune system is specific.

Answer 3

True

Question 4

What defensive antimicrobial enzyme is known to digest bacterial cell walls?

Answer 4

Lysozyme/defensins

Question 5

What is the function of mucous?

Answer 5

Prevent attachment of organisms.

Question 6

Which part of the Innate Immune system is known as “professional killers?”

Answer 6

Neutrophils

Question 7

Which cells are know to capture antigens in one location and present in another?

Answer 7

Dendritic cells

Question 8

T/F: Inflammation is an adaptive immune system cell response.

Answer 8

False; Inflammation is an innate immune cell response.

Question 9

T/F: antibodies kill pathogens.

Answer 9

False, Antibodies mark (opsonize) a target for destruction.

Question 10

What are B cell receptors?

Answer 10

Antibodies

Question 11

What is the basis for immunization?

Answer 11

memory

Question 12

What are the three types of T cells?

Answer 12

helper, killer and regulatory T cells

Question 13

What stimulates proliferation of Tcells and B cells?

Answer 13

cognant antigen

Question 14

What is required by T cells for activation?

Answer 14

Antigen presentation

Question 15

What are the three main antigen presenting cells?

Answer 15

dendritic cells, macrophages, and B cells

Question 16

What does MHC stand for?

Answer 16

Major histocompatibility complex

Question 17

What hormone-like messengers are produced especially by T helper cells and communicate with both immune and non immune cells?

Answer 17

Cytokines

Question 18

interleukins (IL-1, IL-2, etc), interferon y, and TNF (tumor necrosis factor) are examples of what?

Answer 18

Cytokines

Question 19

What type of proteins function as billboards to display chopped up peptides?

Answer 19

MHC (major histocompatibilty complex) proteins

Question 20

Which type of MHC proteins are found on virtually all cells of the body?

Answer 20

Class I

Question 21

Which type of MHC proteins display what cells are producing inside for killer T cells to scan?

Answer 21

Class I

Question 22

Which type of MHC proteins are found typically on APC?

Answer 22

Class II

Question 23

Which type of MHC proteins display what has been killed at the battle site in order to inform T helper cells about the battle?

Answer 23

Class II

Question 24

Which immune system is faster, determines which weapons to be used and has a hard wired memory?

Answer 24

Innate

Question 25

What are the four types of Granulocytes?

Answer 25

Neutrophils, Basophils, Mast cells, and eosinophils

Question 26

Which granulocyte is by far the most common of circulating white blood cells?

Answer 26

Neutrophils

Question 27

What are the different types of Monocytes?

Answer 27

Macrophages and Dendritic cells

Question 28

Which type of monocyte can also arise from lymphoid lineage as well as myeloid lineage?

Answer 28

Dendritic cells

Question 29

Which is the more abundant WBC: Granulocytes or monocytes?

Answer 29

Granulocytes

Question 30

what are the three types of WBCs of lymphoid lineage?

Answer 30

B cells, T cells, and NK cells

Question 31

Which type of lymphoid WBCs are adaptive?

Answer 31

B cells and T cells; NK cells are innate