Intro to equine wound management Flashcards
4 Phases of Wound Healing
- Hemostasis phase
- Inflammatory phase
- Proliferative phase
(i) Fibroplasia
(ii) Angiogenesis
(iii) Epithelialisation
(iv) contraction - Remodelling phase
Hemostasis phase of wound healing
▪Initial vasoconstriction
▪First 5-10 minutes
▪End point: formation of blood clot
Inflammatory phase of wound healing
▪ Also called debridement phase
▪ 1-3 days after injury
Which stage of wound healing do we have the greatest influence on? How?
- the acute inflammatory stage
▪ Debridement
▪ Irrigation
▪Good haemostasis ▪Adequate drainage
^ all greatly hasten wound healing
Proliferative phase of wound healing
▪Filling of the wound bed with healing tissue (fibroblasts)
▪Few days
▪ Lasts for weeks after injury
(i) Fibroplasia
(ii) Angiogenesis
(iii) Epithelialisation
(iv) Contraction
Speed of epithelialisation
▪Slow
▪ flank wounds: rate of 0.2mm/day
▪ limb wounds: rate of 0.09mm/day
What is epithelialisation inhibited by?
▪ infection
▪ desiccation of the wound surface (drying out, therefore bandage choice can impact this stage)
▪ exuberant granulation tissue
▪ repeated dressing changes (every time you change the dressings you’ll take off the top ayer of cells
When does wound contraction start and how long does it last for?
▪ Starts week 2 after wounding
▪ Continues for several weeks
Why is wound contraction important?
▪ Accelerates closure
– Can reduce original SA by 40 to 80%
– Can occur at 0.75mm/day
▪ Increase cosmesis of scar
▪ Less need for epithelialization
Remodelling phase of wound healing
▪ From 2 weeks after wounding
▪Ends in formation of scar tissue one - two years later
▪ Ensure strength, integrity and function of new tissue
Wound healing in ponies (cf horses)
▪1 & 2 intention healing more rapid in ponies
▪Quicker & more intense inflammatory response
▪Pony wounds more resistant to infection
▪Greater contraction due to higher number of leukocytes recruited
▪Less wound dehiscence
▪Fewer bone sequestrate
▪Less exuberant granulation tissue (‘proud flesh’) due to more intense & less prolonged inflammatory phase
Wound prep - clipping
- always clip
- removes foreign material
- makes it easier to stitch
- minimises infection and contamination
- allows much better assessment of the wound
Clipping size
- 5-10cm margin is good
Wound cleaning
▪0.05% chlorhexidine (gluconate) 4%
– Superior antibacterial activity than povidone
iodine
– 12.5 mL in 1L of saline
▪0.1-0.2% povidone iodine
– Inactivated by organic material
– Evidence for dilute povidone iodine use in contaminated wounds
-> 1- 2 mL in 1L of saline
▪OR just water
– Like hose a very contaminated wound down first, to remove the bulk of debris and contamination
– But water itself is toxic to fibroblasts, so you don’t want to clean a wound with water once you’ve got rid of the obvious contamination
(don’t need to remember quantities)
Wound prep order
- Restraint, inc sedation
- Clean and controlled environment (wash box / stable)
- Remove gross contamination
- LA (can usually do digital exploration without but for stitching up and closing a wound need it)
– Bupivicaine, mepivicaine
– Perineural anaesthesia if limb - Gel (KY jelly) and clip (5-10cm margins)
- Remove gel with sterile saline
- Assess