Intro to DPLD Flashcards
What are the four main classifications of ILD?
1) diseases of known cause or association
2) idiopathic interstitial pneumonias
3) granulomatous diseases
4) miscellaneous interstitial diseases
Interstitial lung diseases (ILDs) also go by what name?
diffuse parenchymal lung diseases
What is the defining feature of ILD’s histologically speaking?
Damage to the alveolar wall and interstitium
What is pneumoconiosis?
DPLD of known causes from occupational exposure to inorganic dusts
What is hypersensitivity pneumonitis?
DPLD of known causes from an immunologic response to inhaled organic dusts
DPLDs caused by reactions to chemicals, drugs, radiation and toxic gases or associated with connective tissue diseas fall under what category of DPLD?
known cause
Idiopathic pulmonary fibrosis (IPF) and
Idiopathic nonspecific interstitial pneumonia (NSIP) are what category of idiopathic interstitial pneumonias (IIPs)?
chronic fibrosing
What are the 2 smoking related IIPs
Respiratory bronchiolitis-interstitial lung disease (RB-ILD)
Desquamative interstitial pneumonia (DIP)
What are the 2 acute/subacute IIPs?
Cryptogenic organizing pneumonia (COP)
Acute interstitial pneumonia (AIP)
What is the most common class of idiopathic interstitial pneumonias?
chronic fibrosing IIPs
Sarcoidosis and hypersensitivity pneumonitis are what kind of DPLD?
granulomatous
hypersensitivity is also a DPLD of known cause
What is the most frequent presenting symptom of DPLD?
dyspnea
followed by non productive cough
What is the most common finding on pulmonary exam in DPLD?
inspiratory crackles (especially IPF)
Most ILD’s have what pattern on Xray?
reticular or reticulonodular, typically at the bases
What CXR finding is common in sarcoidosis?
hilar lymphadenopathy