Intro Flashcards
What is the immune system?
A system of cells and molecules designed to fight infection
What barrier do pathogens meet first?
Physical and chemical Barriers
2 types of Immune response are:
Innate and adaptive
Innate Immune response is: 3
Broadly specific, recognises structures shared by many pathogens - same strength and same way every time
Adaptive Immune response is: 3
Highly Ag specific - stronger and faster everytime - immunological memory
5 Properties of skin as a barrier:
- Major line of defence as a protective barrier
- Low pH
- Sweat + sebaceous has inhibitory lactic acid and fatty acids
- Most bacteria fail to survive on skin for too long
- Intact skin is impermeable to most microorganisms
4 Bactericidal body fluids:
Acid in Gastric juice
Spermine and zinc in semen
Lysozyme in tears and saliva and nose
Lactoperoxide in milk
5 immune jobs of mucous:
- Secreted from membranes lining inner surfaces of body
- Protective - stop bacterial adherence to epithelial cells
- Traps microbial and other foreign particles
- Removed by ciliary movement, coughing and sneezing
- Also has chemicals
Microbial antagonism and immunity: 2
Normal flora suppresses grown of pathogenic bacteria and fungi due to competition
If normal flora disturbed - opportunistic infections