Intro Flashcards

1
Q

Which virus has been eradicated?

A

Rinderpest

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2
Q

What is a viroid?

A

particle smaller than any known viruses which is an agent of plant diseases; consists of an extremely small circular RNA with no protein coat

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3
Q

What is a virion?

A

complete virus particle; consists of RNA/DNA core with protein coat; extracellular infective form of a virus

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4
Q

What is a virus?

A

describes any aspect of the infectious agent

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5
Q

What is variolation?

A

aka inoculation
method first used to immunize an individual against smallpox;
used material from a patient or recently variolated individual to produce a mild protective infection

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6
Q

What was Jenner’s important contribution?

A

discovered “vaccination” using cowpox matter to protect against smallpox

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7
Q

What is important about Pasteur?

A

injected dried, potassium hydroxide treated, infected rabbit brain into two boys with rabies and they recovered

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8
Q

What did Chamberland invent?

A

Chamberland filter; has smaller pores than bacteria

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9
Q

Who coined the term “virus”?

A

Beijerinck in 1898; considered to be the beginning of virology

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10
Q

Who first isolated tobacco mosaic virus?

A

Ivanovski

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11
Q

Who discovered the cause of foot and mouth disease?

A

Loeffler and Frosch

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12
Q

Who discovered that yellow fever was spread through mosqueeeeto?

A

Dr. Walter Reed

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13
Q

Who discovered oncogenic viruses?

A

Rous; Rous sarcoma virus

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14
Q

What did Ruska and Knoll invent?

A

electron microscope

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15
Q

What did Woodruff, Goodpasture and Burnet do?

A

propagated fowlpox virus in an embryonated egg

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16
Q

Who first cultured isolated mammalian cells?

A

Sanford et al

17
Q

Who first grew poliovirus in cell culture?

A

Enders et al

18
Q

Who had the first plaque assay for an animal virus?

A

Dulbecco and Vogt